Epithermal neutron beam design for neutron capture therapy at the Power Burst Facility and the Brookhaven Medical Research Reactor
- EG G Idaho, Inc., Idaho Falls, ID (United States). Idaho National Engineering Lab.
Nuclear design studies have been performed for two reactor-based epithermal neutron beams for cancer treatment by neutron capture therapy (NCT). An intermediate-intensity epithermal beam has been designed and implemented at the Brookhaven Medical Research Reactor (BMRR). Measurements show that the BMRR design predictions for the principal characteristics of this beam are accurate. A canine program for research into the biological effects of NCT is now under way at BMRR. The design for a high-intensity epithermal beam with minimal contamination from undesirable radiation components has been finalized for the Power Burst Facility (PBF) at the Idaho National Engineering Laboratory. This design will be implemented when it is determined that human NCT trials are advisable. The PBF beam will exhibit approximately an order of magnitude improvement in absolute epithermal flux intensity over that available in the BMRR, and its angular distribution and spectral characteristics will be more advantageous for NCT. The combined effects of beam intensity, angular distribution, spectrum, and contaminant level allow the desired tumor radiation dose to be delivered in much shorter times than are possible with the currently available BMRR beam, with a significant reduction (factor of 3 to 5) in collateral dose due to beam contaminants.
- DOE Contract Number:
- AC07-76ID01570
- OSTI ID:
- 6992700
- Journal Information:
- Nuclear Technology; (United States), Vol. 92; ISSN 0029-5450
- Country of Publication:
- United States
- Language:
- English
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62 RADIOLOGY AND NUCLEAR MEDICINE
MRR REACTOR
REACTOR EXPERIMENTAL FACILITIES
NEOPLASMS
NEUTRON CAPTURE THERAPY
NEUTRON SOURCES
PBF REACTOR
DESIGN
COMPARATIVE EVALUATIONS
EPITHERMAL NEUTRONS
NEUTRON BEAMS
NEUTRON FLUX
BARYONS
BEAMS
DISEASES
ELEMENTARY PARTICLES
ENRICHED URANIUM REACTORS
EVALUATION
FERMIONS
HADRONS
IRRADIATION REACTORS
ISOTOPE PRODUCTION REACTORS
MEDICINE
NEUTRON THERAPY
NEUTRONS
NUCLEAR MEDICINE
NUCLEON BEAMS
NUCLEONS
PARTICLE BEAMS
PARTICLE SOURCES
PULSED REACTORS
RADIATION FLUX
RADIATION SOURCES
RADIOLOGY
RADIOTHERAPY
REACTOR COMPONENTS
REACTORS
RESEARCH AND TEST REACTORS
RESEARCH REACTORS
TANK TYPE REACTORS
THERAPY
THERMAL REACTORS
WATER COOLED REACTORS
WATER MODERATED REACTORS
220600* - Nuclear Reactor Technology- Research
Test & Experimental Reactors
550603 - Medicine- External Radiation in Therapy- (1980-)