ECUT: Energy Conversion and Utilization Technologies Program: Biocatalysis project: Annual report, FY 1985
This report presents the fiscal year 1985 activities, accomplishments, and planned research efforts of the Biocatalysis Project of the US Department of Energy, Energy Conversion and Utilization Technologies Program. In the Molecular Moedling and Applied Genetics work element, research focused on modeling and simulation studies to establish the physiological basis of high temperature tolerance in a selected enzyme and the catalytic mechanisms of three species of another enzyme, and on determining the degree of plamid amplification and stability of several DNA bacterial strains where the DNA plasmid had been inserted directly into the bacterial chromosome. In the Bioprocess Engineering work element, research focused on studies of plasmid propagation and the generation of models for plasmid replification and gene expression control in recombinant microorganisms, on developing methods for preparing immobilized biocatalyst beads for use in a fluidized bed reactor system, and on developing an enzyme encapsulation method for suspension in non-aqueous solutions. In the Process Design and Analysis work element research focused on further refinement of a test case simulation of the economics and energy efficiency of alternative biocatalyzed production processes, on developing a candidate bioprocess to determine potential for reduced energy consumption and facility/operating costs, and on a techno-economic assessment of potential advancements in microbial ammonia production.
- Research Organization:
- Jet Propulsion Lab., Pasadena, CA (USA)
- DOE Contract Number:
- AI01-81CS66001
- OSTI ID:
- 6983857
- Report Number(s):
- DOE/CS/66001-9; JPL-PUB-86-32; ON: DE87005233
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
BIOCHEMICAL REACTION KINETICS
MATHEMATICAL MODELS
ENZYMES
RESEARCH PROGRAMS
ESCHERICHIA COLI
GENETIC ENGINEERING
GENE AMPLIFICATION
RECOMBINANT DNA
SACCHAROMYCES CEREVISIAE
ZYMOMONAS MOBILIS
BIOREACTORS
CELL FLOW SYSTEMS
COMPUTERIZED CONTROL SYSTEMS
ENZYME ACTIVITY
IMMOBILIZED ENZYMES
PLASMIDS
PROCESS DEVELOPMENT UNITS
PROGRAM MANAGEMENT
BACTERIA
CELL CONSTITUENTS
CONTROL SYSTEMS
DNA
FUNCTIONAL MODELS
FUNGI
KINETICS
MANAGEMENT
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PLANTS
REACTION KINETICS
SACCHAROMYCES
YEASTS
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