Influence of intoxication with vanadium compounds on the intestinal absorption of calcium in the rat

Journal Article · Mon Dec 01 00:00:00 EST 1986 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01607856· OSTI ID:6787928

Witkowska, D; Oledzka, R; Pietrzyk, B

Calcium is transferred to the plasma after absorption from the gastrointestinal tract and by resorption from the bone. It is recognized that many environmental poisons, e.g. heavy metal, pesticides etc. cause alterations in calcium homeosthasis in human beings and experimental animals. Although vanadium is not considered to be as important a health hazard to man as lead or cadmium it must be nevertheless regarded as a dangerous pollutant. There exists an obvious risk of pollution by and poisoning due to the high vanadium content of crude oil and the industrial use of vanadium as a steel additive. The toxic effects of this element and its compounds in many biological systems have been reviewed in detail but little is known about vanadium influence on calcium metabolism. The present study was undertaken to determine the effect of various treatments with vanadium compounds, containing vanadium as VO/sup 2 +/ (VOSO/sub 4/) and VO/sub 3/ (NaVO/sub 3/) ions, exert on calcium transport through the rat duodenum.

• Research Organization: Institute of Biopharmacy, Warsaw, Poland
• OSTI ID: 6787928
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Vol. 37:6
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
62 RADIOLOGY AND NUCLEAR MEDICINE
CALCIUM 45
TISSUE DISTRIBUTION
CALCIUM COMPOUNDS
INTESTINAL ABSORPTION
VANADATES
BIOLOGICAL EFFECTS
VANADIUM SULFATES
ACUTE EXPOSURE
CHRONIC EXPOSURE
FEMUR
KIDNEYS
LIVER
ORAL ADMINISTRATION
RATS
SMALL INTESTINE
SODIUM COMPOUNDS
ABSORPTION
ALKALI METAL COMPOUNDS
ALKALINE EARTH ISOTOPES
ALKALINE EARTH METAL COMPOUNDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CALCIUM ISOTOPES
DAYS LIVING RADIOISOTOPES
DIGESTIVE SYSTEM
DISTRIBUTION
EVEN-ODD NUCLEI
GASTROINTESTINAL TRACT
GLANDS
INTERMEDIATE MASS NUCLEI
INTESTINES
ISOTOPES
MAMMALS
NUCLEI
ORGANS
OXYGEN COMPOUNDS
RADIOISOTOPES
RODENTS
SKELETON
SULFATES
SULFUR COMPOUNDS
TRANSITION ELEMENT COMPOUNDS
UPTAKE
VANADIUM COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
550601 - Medicine- Unsealed Radionuclides in Diagnostics