Stereo x-ray photogrammetry applied for prevention of sigmoid-colon damage caused by radiation from intrauterine sources
Radiation therapy of cervix carcinoma is applied in this Institute by means of modified Stockholm method in combination with external beam irradiation. In 1968, parametrial portals were replaced by large planeparallel opposed fields extending cranially to LIII/LIV with central shielding in order to avoid overdosage in the area of intracavitary treatment. This resulted in a marked increased incidence of serere sigmoid-colon radiation lesions from 0.25% to 4%; predominantly in Stage I and II patients. Therefore two measures have been introduced: beginning in 1972 measures were taken to prevent the cranial displacement of the uterus during intracavitary treatment in order to avoid shortening the distance between the radioactive sources and the sigmoid-colon; from 1973 stereo X ray photogrammetry (SRM) was applied for dose determinations at points of the sigmoid-colon, which were seen to be located close to the applicator. When SRM data indicated that a high dose at the sigmoid-colon might occur, treatment modifications enabled prevention of radiation damage. Change of position of the applicator was the first to be considered. In the last seven years no surgical intervention had to be performed because of a sigmoid-colon lesion resulting from an unexpected high radiation dose delivered by intrauterine sources. The local recurrence rate was not increased following treatment modifications for prevention of sigmoid-colon radiation damage.
- OSTI ID:
- 6714371
- Journal Information:
- Int. J. Radiat. Oncol., Biol. Phys.; (United States), Vol. 8:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
RADIOTHERAPY
DOSIMETRY
SIDE EFFECTS
UTERUS
BIOLOGICAL RADIATION EFFECTS
CARCINOMAS
EXTERNAL IRRADIATION
HARD X RADIATION
LARGE INTESTINE
PHOTOGRAPHY
RADIATION SOURCE IMPLANTS
BIOLOGICAL EFFECTS
BODY
DIGESTIVE SYSTEM
DISEASES
ELECTROMAGNETIC RADIATION
FEMALE GENITALS
GASTROINTESTINAL TRACT
IMPLANTS
INTESTINES
IONIZING RADIATIONS
IRRADIATION
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIATION SOURCES
RADIATIONS
RADIOLOGY
THERAPY
X RADIATION
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)