Role of gallium 67 in inflammatory disease. [/sup 99m/Tc]

Journal Article · Sat Jul 01 00:00:00 EDT 1978 · Semin. Nucl. Med.; (United States)

DOI:https://doi.org/10.1016/S0001-2998(78)80030-0· OSTI ID:6670711

Staab, E V; McCartney, W H

Gallium-67 citrate has been found to be extremely useful for detection of inflammatory disease. In the skeletal system it complements the /sup 99m/Tc-phosphate compounds in differentiating periarticular osteomyelitis, septic arthritis, and cellulitis. Gallium is particularly useful in documenting successful treatment of bone infection because the phosphate scan remains positive for much longer periods of time. In a variety of chest disorders gallium uptake has been found to correlate well with the active inflammatory state. One of the most frequent uses of gallium imaging has been for localization of inflammatory foci in postoperative patients as well as in patients who present with fever of undetermined origin. Neutropilic labeling followed by migration to the inflammatory area appears to be the major mechanism of localization of radiogallium. For this reason leukopenic patients constitute a group in which false negative results may be encountered.

• Research Organization: Univ. of North Carolina, Chapel Hill
• OSTI ID: 6670711
• Journal Information: Semin. Nucl. Med.; (United States), Vol. 8:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE TISSUES
SCINTISCANNING
GALLIUM
INFLAMMATION
DIAGNOSIS
SKELETAL DISEASES
TECHNETIUM 99
ISOMERIC NUCLEI
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CONNECTIVE TISSUE
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
METALS
NUCLEI
ODD-EVEN NUCLEI
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
TISSUES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics