ESR study of radiation-induced radicals in the sugar-phosphate region of nucleotides. III. The alkoxy radical in deoxycytidine 5'-phosphate
The unstable radical at 77 K in a gamma-irradiated single crystal of deoxycytidine 5'-phosphate was analyzed by ESR. A very anisotropic g tensor (g/sub 1/=1.9997, g/sub 2/=2.0095, and g/sub 3/=2.0773) and two approximately equal ..beta..-proton couplings with isotropic values of 8.0 G were interpreted to represent a radical of the O--CH/sub 2/--R form. The radical is formed by the breakage of the phosphate--ester bond. The calculated spin densities on H/sub() 5prime/ and H'/sub() 5prime/ in the INDO MO approximation are in agreement with the observed couplings. The lack of any hydrogen bonding in the radical is believed to bring about much smaller ..beta..-proton couplings from those previously observed and assigned to the same radical.
- Research Organization:
- Faculty of Medicine, University of Zagreb, Zagreb, Croatia, Yugoslavia
- OSTI ID:
- 6670535
- Journal Information:
- J. Chem. Phys.; (United States), Vol. 69:6
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
ALKOXY RADICALS
ELECTRON SPIN RESONANCE
NUCLEIC ACIDS
RADIOLYSIS
GAMMA RADIATION
MONOCRYSTALS
CHEMICAL RADIATION EFFECTS
CHEMICAL REACTIONS
CHEMISTRY
CRYSTALS
DECOMPOSITION
ELECTROMAGNETIC RADIATION
IONIZING RADIATIONS
MAGNETIC RESONANCE
ORGANIC COMPOUNDS
RADIATION CHEMISTRY
RADIATION EFFECTS
RADIATIONS
RADICALS
RESONANCE
560110* - Radiation Effects on Biochemicals- (-1987)
400600 - Radiation Chemistry