Induced chirality of polycyclic aromatic hydrocarbons in aqueous bile salt solutions

Conference · Mon Jan 01 00:00:00 EST 1990 · American Chemical Society, Division of Environmental Chemistry, Preprints; (USA)

OSTI ID:6617203

Wu, K; Williamson, C K; McGown, L B ^[1]

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1. Duke Univ., Durham, NC (USA)

We will discuss the effects of organized bile salt phases on the chirality of several polycyclic aromatic hydrocarbons (PAHs), as investigated by transmission circular dichroism (CD) and fluorescence-detected circular dichroism (FDCD). Amphiphilic bile salt monomers form chiral micellar aggregates and should induce interesting changes in the chirality of the PAH probes. The high sensitivity of FDCD allows us to examine the effects of the organized bile salt media on the probe molecule over a large range of concentrations both above and below the critical micelle concentration (cmc) of the bile salt. The use of chiral bile salt media for FDCD determination of fluorescent analytes will be discussed.

• OSTI ID: 6617203
• Report Number(s): CONF-900402-; CODEN: ACEPC
• Journal Information: American Chemical Society, Division of Environmental Chemistry, Preprints; (USA), Vol. 30:1; Conference: 199. national meeting of the American Chemical Society, Boston, MA (USA), 22-27 Apr 1990; ISSN 0093-3066
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
POLYCYCLIC AROMATIC HYDROCARBONS
CHIRALITY
BILE ACIDS
BIOCHEMISTRY
MEASURING INSTRUMENTS
MEASURING METHODS
PROCEEDINGS
AROMATICS
CARBOXYLIC ACIDS
CHEMISTRY
DOCUMENT TYPES
HYDROCARBONS
HYDROXY COMPOUNDS
ORGANIC ACIDS
ORGANIC COMPOUNDS
PARTICLE PROPERTIES
STEROIDS
STEROLS
551000* - Physiological Systems