Erythrocyte survival following intraoperative autotransfusion in spinal surgery: an in vivo comparative study and 5-year update
A 5-year prospective study of intraoperative blood transfusion in 239 patients, most of whom had major spinal surgery, has been completed. Autotransfusion is safe, practical, and it reduces donor blood requirements and total blood loss by 50%. It eliminates host versus graft reactions and disease transmission. In 33 patients having major spinal surgery, the in vivo survival of autologous, homologous, and processed red blood cells (RBC) using the Cell Saver System were compared. The RBC survival studies were performed using chromium-51 isotope labeling technique. The long-term survival of processed RBCs was normal over a 30-day period. There was no significant difference in the survival rate of the three groups studied.
- Research Organization:
- Orlando Regional Medical Center, FL
- OSTI ID:
- 6576734
- Journal Information:
- Spine (Hagerstown, Md.); (United States), Vol. 9
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
BLOOD
TRANSFUSIONS
ERYTHROCYTES
SURVIVAL CURVES
VERTEBRAE
SURGERY
CHROMIUM 51
COMPARATIVE EVALUATIONS
IN VIVO
PATIENTS
TRACER TECHNIQUES
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD CELLS
BODY
BODY FLUIDS
CHROMIUM ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MATERIALS
MEDICINE
NUCLEI
ORGANS
RADIOISOTOPES
SKELETON
THERAPY
550600* - Medicine
550301 - Cytology- Tracer Techniques