Energy deposition and radiation quality of radon and radon daughters. Final report
This program was aimed at creating a quantitative physical description, at the micrometer and nanometer levels, of the physical interactions of the alpha particles from radon and its daughters with cells at risk in the bronchial epithelium. The authors calculated alpha-particle energy spectra incident upon the cells and also energy deposition spectra in micrometer- and nanometer-sized sites as a function of cell depth, site size, airway diameter, activities of {sup 218}Po and {sup 214}Po, and other parameters. These data are now being applied, using biophysical models of radiation effects, to predict cell killing, mutations, and cell transformation. The model predictions are then compared to experimental biophysical, biochemical, and biological information. These studies contribute to a detailed understanding of the mechanisms of the biological effectiveness of the radiations emitted by radon and its progeny.
- Research Organization:
- National Inst. of Standards and Technology, Gaithersburg, MD (United States)
- Sponsoring Organization:
- USDOE Office of Energy Research, Washington, DC (United States)
- DOE Contract Number:
- AI02-93ER61599
- OSTI ID:
- 656480
- Report Number(s):
- DOE/ER/61599-T1; ON: DE98006370; TRN: 99:000470
- Resource Relation:
- Other Information: PBD: 9 Sep 1996
- Country of Publication:
- United States
- Language:
- English
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