The CEPH consortium linkage map of human chromosome 15q

Journal Article · Tue Dec 01 00:00:00 EST 1992 · Genomics; (United States)

DOI:https://doi.org/10.1016/S0888-7543(05)80101-6· OSTI ID:6483418

Bowcock, A M; Barnes, R I ^[1]; White, R L ^[2]; Kruse, T A ^[3]; Tsipouras, P; Sarfarazi, M ^[4]; Litt, M; Kramer, P L ^[5]; Jenkins, T; Viljoen, C ^[6]

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1. Univ. of Texas Southwestern Medical Center, Dallas, TX (United States)
2. Univ. of Utah Medical Center, Salt Lake City, UT (United States)
3. Aarhus Universitet (Denmark)
4. Univ. of Connecticut Health Center, Farmington, CT (United States)
5. Oregon Health Sciences Univ., Portland, OR (United States)
6. and others

The CEPH consortium map of chromosome 15q is presented. The map contains 41 loci defined by genotypes generated from CEPH family DNAs with 45 different probe and restriction enzyme combinations contributed by 10 laboratories. A total of 29 loci have been placed on the map with likelihood support of at least 1000:1. The map extends from 15q13 to 15q25-qter. Multipoint linkage analyses provided estimates that the male, female, and sex-averaged maps extend for 127, 190, and 158 cM, respectively. The largest interval is 21 cM and is between D15S37 and D15S74. The on-average locus spacing is 5.6 cM and the mean genetic distance between the 21 uniquely placed loci is 8 cM. 61 refs., 1 fig., 4 tabs.

• OSTI ID: 6483418
• Journal Information: Genomics; (United States), Vol. 14:4; ISSN 0888-7543
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
HUMAN CHROMOSOME 15
GENETIC MAPPING
DNA HYBRIDIZATION
STATISTICS
BIOTECHNOLOGY
CHROMOSOMES
GENETIC ENGINEERING
HUMAN CHROMOSOMES
HYBRIDIZATION
MAPPING
MATHEMATICS
NUCLEIC ACID HYBRIDIZATION
550400* - Genetics