Research in radiobiology: Annual report of work in progress in the internal irradiation program

Technical Report · Thu Dec 31 00:00:00 EST 1987

OSTI ID:6466423

Miller, S C; Buster, D S ^[1]

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1. eds.

In the early 1950's the Atomic Energy Commission established at the University of Utah a large, long-term study designed to investigate the toxicity of internally deposited radionuclides in beagles. The first animals were injected on December 1, 1952 and thus began an odyssey unusual in modern science both for its duration and continued scientific interest and relevance. The original dogs were injected with /sup 239/Pu and /sup 226/Ra. Later, studies were initiated with /sup 241/Am, /sup 249/Cf, /sup 252/Cf, /sup 253/Es, /sup 224/Ra, /sup 228/Ra, /sup 90/Sr, and /sup 228/Th. These studies were unique and have and will continue to contribute valuable scientific information on the behavior and effects of these substances in biological systems. We feel that the data collected from these studies will be useful for many decades to come as we ask more demanding questions relative to radionuclides and environmental, biological and health issues. While this publication will be the last of our series Research in Radiobiology, the lifespan carcinogenesis studies are continuing under a collaborative arrangement with the I.T.R.I. Beginning in 1988, the colony status tables of dogs in the Utah studies and reports of research by the Radiobiology faculty will be included in the annual I.T.R.I. report. Under our new collaborative arrangements with the I.T.R.I. for the conduct of the lifespan carcinogenesis studies, we expect a continued high level of scientific productivity from our faculty.

• Research Organization: Utah Univ., Salt Lake City (USA). Radiobiology Div.
• DOE Contract Number: AC02-76EV00119
• OSTI ID: 6466423
• Report Number(s): DOE/EV/00119-T3; COO-119-263; ON: DE89009046; TRN: 89-008794
• Resource Relation: Other Information: Portions of this document are illegible in microfiche products
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
UTAH
RESEARCH PROGRAMS
AMERICIUM 241
BEAGLES
CALIFORNIUM 249
CALIFORNIUM 252
EINSTEINIUM 253
LIFE SPAN
MORTALITY
PLUTONIUM 239
PROGRESS REPORT
RADIATION EFFECTS
RADIOBIOLOGY
RADIUM 224
RADIUM 226
RADIUM 228
STRONTIUM 90
THORIUM 228
ACTINIDE ISOTOPES
ACTINIDE NUCLEI
ALKALINE EARTH ISOTOPES
ALPHA DECAY RADIOISOTOPES
AMERICIUM ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGY
CALIFORNIUM ISOTOPES
CARBON 14 DECAY RADIOISOTOPES
DAYS LIVING RADIOISOTOPES
DOCUMENT TYPES
DOGS
EINSTEINIUM ISOTOPES
EVEN-EVEN NUCLEI
EVEN-ODD NUCLEI
FEDERAL REGION VIII
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
ISOTOPES
MAMMALS
NORTH AMERICA
NUCLEI
ODD-EVEN NUCLEI
PLUTONIUM ISOTOPES
RADIOISOTOPES
RADIUM ISOTOPES
STRONTIUM ISOTOPES
THORIUM ISOTOPES
USA
VERTEBRATES
YEARS LIVING RADIOISOTOPES
560150* - Radiation Effects on Animals