Air-sampling and analytical method for 4,4'-methylenebis(2-chloroaniline)

Journal Article · Mon Jan 01 00:00:00 EST 1979 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac50037a012· OSTI ID:6436147

Rappaport, S M; Morales, R

A sampling and analytical method is described for the determination of airborne exposures of individuals to the carcinogen, 4,4'-methylenebis(2-chloroaniline), known as MOCA. The personal sampler employs a filter to collect particulate MOCA followed by a bed of silica gel to remove the vapors. MOCA is extracted from the sampler stages with methanol and a 10-..mu..L aliquot is injected into an HPLC operating with a reverse-phase system. The UV detector (254 nm) allows quantitation of 3 ng of MOCA corresponding to 0.15 ..mu..g/sample. Precision levels were determined to be 9.2% at 1.5 ..mu..g/sample and 14% at 0.15 ..mu..g/sample. 7 figures, 3 tables..

• Research Organization: Univ. of California, Los Alamos, NM
• OSTI ID: 6436147
• Journal Information: Anal. Chem.; (United States), Vol. 51:1
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
AEROSOLS
MONITORING
AIR POLLUTION
AMINES
QUANTITATIVE CHEMICAL ANALYSIS
ORGANIC CHLORINE COMPOUNDS
AIR SAMPLERS
CARCINOGENS
FILTERS
LIQUID COLUMN CHROMATOGRAPHY
MEDIUM PRESSURE
MEDIUM TEMPERATURE
METHANOL
PRESSURE DEPENDENCE
SENSITIVITY
SEPARATION PROCESSES
SILICA GEL
SOLVENT EXTRACTION
TEMPERATURE DEPENDENCE
TRACE AMOUNTS
ULTRAVIOLET SPECTRA
ADSORBENTS
AIR POLLUTION MONITORS
ALCOHOLS
CHEMICAL ANALYSIS
CHROMATOGRAPHY
COLLOIDS
DISPERSIONS
EXTRACTION
HYDROXY COMPOUNDS
LABORATORY EQUIPMENT
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
POLLUTION
SAMPLERS
SOLS
SPECTRA
500200* - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)
560306 - Chemicals Metabolism & Toxicology- Man- (-1987)
400102 - Chemical & Spectral Procedures