Use of preoperative localization of adenomas of the parathyroid glands by thallium-technetium subtraction scintigraphy, high-resolution ultrasonography and computed tomography

Journal Article · Wed Feb 01 00:00:00 EST 1989 · Surg. Gynecol. Obstet.; (United States)

OSTI ID:6406831

Roses, D F; Sudarsky, L A; Sanger, J; Raghavendra, B N; Reede, D L; Blum, M

Thirty-six patients with primary hyperparathyroidism were studied preoperatively by thallium-201 and technetium-99m pertechnetate subtraction (Tl-201/Tc-99m) scintigraphy, high-resolution real time ultrasonography and computed tomographic (CT) scanning. None of the patients had had previous surgical treatment of the parathyroid or thyroid glands. All of the patients underwent systematic bilateral exploration of the neck. All of the patients were successfully explored and 41 abnormal parathyroid glands were identified. Five patients had two adenomas. In six instances, adenomas were identified in ectopic anatomic sites. The sensitivity of correctly localizing the abnormal glands with these techniques was 49 per cent for the Tl-201/Tc-99m scintigraphy, 34 per cent for ultrasonography and 41 per cent for CT scanning. The Tl-201/Tc-99m scintigrams detected two of the six ectopically located adenomas, CT detected one, while ultrasound detected none. The five patients with multiple adenomas were not accurately identified as having multiple gland enlargement by any of these studies. Therefore, preoperative localization studies with these three techniques did not provide reliable information for initial bilateral exploration of the neck.

• Research Organization: New York Univ. Medical Center, NY (USA)
• OSTI ID: 6406831
• Journal Information: Surg. Gynecol. Obstet.; (United States), Vol. 168:2
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ADENOMAS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
COMPARATIVE EVALUATIONS
PARATHYROID GLANDS
COMPUTERIZED TOMOGRAPHY
DUAL-ISOTOPE SUBTRACTION TECHNIQUE
HYPERPARATHYROIDISM
ISOMERIC NUCLEI
PATIENTS
SCINTISCANNING
SENSITIVITY ANALYSIS
TECHNETIUM 99
THALLIUM 201
ULTRASONOGRAPHY
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
TECHNETIUM ISOTOPES
THALLIUM ISOTOPES
TOMOGRAPHY
TRACER TECHNIQUES
YEARS LIVING RADIOISOTOPES
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