Correlation of isotopic cisternographic patterns in multiple sclerosis with CSF IgG values

Journal Article · Mon Nov 01 00:00:00 EST 1982 · Ann. Neurol.; (United States)

DOI:https://doi.org/10.1002/ana.410120514· OSTI ID:6306061

Bartolini, S; Inzitari, D; Castagnoli, A; Amaducci, L

Thirty-eight patients with multiple sclerosis (MS) were examined with isotopic cisternography (IC) in order to study cerebrospinal fluid (CSF) dynamics. Cisternography was also performed in 15 patients with amyotrophic lateral sclerosis and in 14 with senile dementia of the Alzheimer type as controls. IC pattern of ''mixed'' type was found in 18 MS patients and all those with Alzheimer senile dementia examined, while the IC examination did not show abnormality in any of 15 patients with amyotrophic lateral sclerosis. In MS patients, the abnormal IC picture proved to be significantly correlated with the CSF IgG values as calculated by Link's and Tourtelotte's formulas. The abnormal IC in MS may be due to altered CSF reabsorption or increased transependymal flow, or it may be related to the abnormal concentration of IgG.

• Research Organization: Department of Neurology, University of Florence, Italy
• OSTI ID: 6306061
• Journal Information: Ann. Neurol.; (United States), Vol. 12:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
SKELETAL DISEASES
PATHOLOGY
SKELETON
COMPUTERIZED TOMOGRAPHY
ANTIBODIES
BIOCHEMISTRY
CEREBROSPINAL FLUID
PATIENTS
BIOLOGICAL MATERIALS
BODY
BODY FLUIDS
CHEMISTRY
DIAGNOSTIC TECHNIQUES
DISEASES
MATERIALS
ORGANS
TOMOGRAPHY
550602* - Medicine- External Radiation in Diagnostics- (1980-)