Determining the mutagenic potential of environmental agents of importance of man using mammalian, microbial, and Drosophila procedures. Final progress report

Technical Report · Fri Jan 01 00:00:00 EST 1982

OSTI ID:6218383

This progress report is divided into two major sections. The first section has to do with evaluation of several fly ashes in a series of in vitro and animal tests. The tests include in vivo cytogenetic studies including the micronucleus and metaphase analysis assays, in vitro tests for microbial activity using the Salmonella tester strains, evaluation of urine from treated animals for the presence of mutagenic compounds, in vitro transformation assay and an analysis of lung tissue damage following inhalation studies. The second section deals with the development of statistical methodology for the cell transformation assay and the mouse micronucleus assay.

• Research Organization: Texas Univ., Galveston (USA). Medical Branch
• DOE Contract Number: AS05-78EV06023
• OSTI ID: 6218383
• Report Number(s): DOE/EV/06023-T1; ON: DE83012572
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ONCOGENIC TRANSFORMATIONS
MUTAGEN SCREENING
BIOASSAY
MUTAGENESIS
BIOLOGICAL EFFECTS
FLY ASH
IN VITRO
IN VIVO
INHALATION
LUNGS
MAMMALS
PATHOLOGICAL CHANGES
STATISTICS
AEROSOL WASTES
ANIMALS
ASHES
BODY
INTAKE
MATHEMATICS
ORGANS
RESIDUES
RESPIRATORY SYSTEM
SCREENING
VERTEBRATES
WASTES
560301* - Chemicals Metabolism & Toxicology- Cells- (-1987)