Use of HPLC for the analytical determination of diisocyanates and acid anhydrides in the air of working environments

Journal Article · Sat Jun 01 00:00:00 EDT 1985 · Anal. Lett.; (United States)

DOI:https://doi.org/10.1080/00032718508066202· OSTI ID:6178082

Rietz, B

Measurements of airborne concentrations of (monomeric) 2,4- and 2,6- toluene diisocyanate (2,4- and 2,6- TDI), 4,4' - diisocyanato diphenylmethane (MDI) and phthalic anhydride have been performed at 17 Danish atmanufactories using these compounds in the production of polyurethane foams, insulating materials, elastomers, coatings, lacquers and glues. Diisocyanate vapors at workplaces were collected in impingers, containing a solution of 9-(N-methylaminomethyl)-anthracene (1 x 10/sup -4/ M) in toluene. By reaction with this amine compounds the diisocyanates are converted to stable urea derivatives. Phthalic anhydride particles were collected on glass fiber filters. For separation and detection of the diisocyanate derivatives and the phthalic acid formed upon hydrolysis of its anhydride, reversed phase high performance liquid chromatography on a bonded octadecylsilyl phase using isocratic elution with acetonitrile/water and UV-monitoring at lambda = 254 nm were used. The results obtained for each manufacturer are presented. 2 references, 3 figures, 1 table.

• Research Organization: Danish National Institute of Occupational Health, Hellerup
• OSTI ID: 6178082
• Journal Information: Anal. Lett.; (United States), Vol. 18:A10
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
54 ENVIRONMENTAL SCIENCES
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
AIR
FILTRATION
QUANTITATIVE CHEMICAL ANALYSIS
ANHYDRIDES
DERIVATIZATION
LIQUID COLUMN CHROMATOGRAPHY
ISOCYANATES
PARTICULATES
AIR POLLUTION
AIR POLLUTION MONITORING
AIR QUALITY
EXPERIMENTAL DATA
FILTERS
WORKING CONDITIONS
CHEMICAL ANALYSIS
CHEMICAL REACTIONS
CHROMATOGRAPHY
DATA
ENVIRONMENTAL QUALITY
FLUIDS
GASES
INFORMATION
NUMERICAL DATA
PARTICLES
POLLUTION
SEPARATION PROCESSES
400102* - Chemical & Spectral Procedures
500200 - Environment
Atmospheric- Chemicals Monitoring & Transport- (-1989)
570000 - Health & Safety