In-utero carbon monoxide poisoning and multiple fetal abnormalities
- Free Univ. of Brussels (Belgium). Queen Fabiola Children's Hospital
Carbon monoxide (CO) poisoning during pregnancy can lead to feto-maternal fatalities and stillbirths. Teratogenic effects have been reported. The authors strongly suspected an association between mild but chronic CO poisoning of the mother and major multiple malformations in the baby. Retrospective interviews of the mother disclosed that at 10 weeks' gestation, she had complained of headache and dizziness. At the same time, her 16-month-old daughter had an episode of unconsciousness. A faulty kitchen gas water-heater was suspected but the family did not have it repaired. The mother continued to have headaches regularly. During the 7th month of pregnancy, the daughter was found comatose. In the emergency ward, carboxyhemoglobins levels were 27.5% for the child and 14% for the pregnant mother. Both were treated with hyperbaric oxygen. Investigations by the gas company revealed a highly abnormal CO production from the kitchen and bathroom gas-water heaters: 120 and 100 parts per million, respectively, after 2 minutes of use.
- OSTI ID:
- 6143114
- Journal Information:
- Lancet; (United States), Vol. 341:8839; ISSN 0099-5355
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
54 ENVIRONMENTAL SCIENCES
CARBON MONOXIDE
ECOLOGICAL CONCENTRATION
TERATOGENESIS
FETUSES
MALFORMATIONS
AIR POLLUTION MONITORING
GAS APPLIANCES
INDOOR AIR POLLUTION
LEAKS
MAN
AIR POLLUTION
ANIMALS
APPLIANCES
CARBON COMPOUNDS
CARBON OXIDES
CHALCOGENIDES
EQUIPMENT
MAMMALS
MONITORING
OXIDES
OXYGEN COMPOUNDS
PATHOLOGICAL CHANGES
POLLUTION
PRIMATES
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
540120 - Environment
Atmospheric- Chemicals Monitoring & Transport- (1990-)