Gallium scan for detecting Pneumocystic Carinii pneumonitis in patients with acquired immunodeficiency syndrome (AIDS)
Pneumocystic carinii pneumonitis (PCP) is one of the common causes of death in patients with AIDS. Bronchoscopy with washing and transbronchial biopsy are necessary for diagnosis of PCP, however, they are invasive procedures. Forty Ga-67 scans were performed in 33 male patients (age 18-53) with AIDS to evaluate the possibility of PCP infection. Multiple projections over the thorax were obtained at 24-48 and/or 72 hr. after IV of 3 mCi of Ga-67. The positive Ga scans included 15 with diffuse lung activity (7 homogeneous and 8 inhomogeneous), 7 with focal lung activity and 3 with hilar activity. When using the criteria of Ga activity approx. = 2+ represents PCP, the sensitivity and specificity were 92% and 83% respectively. The authors conclude that the Ga lung scan in PCP may present as both focal or diffuse involvement, is a sensitive non-invasive test for detecting PCP in pts with AIDS and thus it may be useful in AIDS pts when PCP is suspected.
- Research Organization:
- LAC/USC Medical Center, Los Angeles, CA
- OSTI ID:
- 5976083
- Report Number(s):
- CONF-850611-; TRN: 87-039209
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 26:5; Conference: 32. annual meeting of the Society of Nuclear Medicine, Houston, TX, USA, 2 Jun 1985
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
AIDS
CHEST
SCINTISCANNING
GALLIUM 67
DIAGNOSTIC USES
LUNGS
RESPIRATORY SYSTEM DISEASES
DIAGNOSIS
PATIENTS
PNEUMONITIS
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM ISOTOPES
HEMIC DISEASES
INFECTIOUS DISEASES
INTERMEDIATE MASS NUCLEI
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
USES
VIRAL DISEASES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques