Carcinoma of the endometrium with cervical involvement (Stage II). [Treatment results and complications]
Between September 1968 and December 1976, 88 patients with Stage II endometrial carcinoma underwent treatment. They were subclassified according to microscopic or gross cervical involvement. Five different types of treatment were administered as follows: (a) preoperative external irradiation and intracavitary radium application followed by total abdominal hysterectomy and bilateral salpingo-oophorectomy; (b) radical radiotherapy alone; (c) radical radiotherapy with external irradiation and intracavitary application; (d) external irradiation and intracavitary radium followed by simple hysterectomy; and (e) postoperative treatment with external irradiation and vaginal radium for patients referred after hysterectomy. Hysterograms performed in 33 patients showed tumor arising in the fundus and extending to the cervix, and hysterograms performed in 8 patients showed tumor arising in the lower segment of the fundus. Pathologically, once the cervix became involved, there was always some degree of myometrial involvement. The preoperative microscopically involved group and the postoperative group demonstrated similar survival rates, as did the radical radiotherapy group with microscopic involvement and the group with gross cervical involvement, with a follow-up period of at least one year in all groups. Surgical findings, pathological findings, and results are analyzed in detail by treatment group.
- Research Organization:
- Tufts-New England Medical Center, Boston, MA
- OSTI ID:
- 5966344
- Journal Information:
- Cancer; (United States), Vol. 43:6
- Country of Publication:
- United States
- Language:
- English
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