Calculation of right and left ventricular ejection fraction using first pass and gated blood-pool scans

Journal Article · Sun Sep 01 00:00:00 EDT 1985 · J. Nucl. Med. Technol.; (United States)

OSTI ID:5930841

Little, L; Osbakken, M

Right and left ventricular (RV, LV) ejection fractions (EF) were calculated from first-pass and gated blood-pool scans in 19 patients with different cardiac diseases and in 5 normal subjects. Both types of scans were obtained after a single adequate bolus injection of technetium pertechnetate. Ejection-fractions from both data collection modes were calculated with a combination of threshold and second derivative computer algorithms. Right ventricular ejection fraction (RVEF) by first-pass technique was 25 +/- 11.7 (mean +/- s.d.) for patients and 29 +/- 2.9 for controls; and by gated equilibrium scan was 34 +/- 10.3 for patients and 31 +/- 0.9 for controls. Left ventricular ejection fraction (LVEF) by first pass was 28 +/- 11.9 for patients and 38 +/- 9.6 for controls; and by gated equilibrium scan was 40 +/- 12 for patients and 62 +/- 8.9 for controls. Ejection fraction data from first-pass and gated equilibrium scans were analyzed with linear regression techniques. The correlation coefficient for RVEFs by the two methods was 0.46 for patients and 0.99 for controls; for LVEFs it was 0.63 for patients and -0.11 for controls. Although both of these values for patients were statistically significant, there was wide scatter between EF values obtained with the two methods in the patient group and in the control group for LVEFs. Thus, one method cannot be substituted for the other to provide reproducible and reliable information concerning RV and LV function in patients with cardiac disease, or for LV function in the controls.

• Research Organization: Milton S. Hershey Medical Center, PA
• OSTI ID: 5930841
• Journal Information: J. Nucl. Med. Technol.; (United States), Vol. 13:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
HEART
DYNAMIC FUNCTION STUDIES
SCINTISCANNING
TECHNETIUM 99
DIAGNOSTIC USES
CARDIOVASCULAR DISEASES
ETIOLOGY
GAMMA CAMERAS
IMAGE PROCESSING
ISOMERIC NUCLEI
PATIENTS
PERTECHNETATES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
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CAMERAS
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISEASES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OXYGEN COMPOUNDS
PROCESSING
RADIOISOTOPE SCANNING
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REFRACTORY METAL COMPOUNDS
TECHNETIUM COMPOUNDS
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550601* - Medicine- Unsealed Radionuclides in Diagnostics