Radionuclide transit: a sensitive screening test for esophageal dysfunction

Journal Article · Fri May 01 00:00:00 EDT 1981 · Gastroenterology; (United States)

OSTI ID:5926074

Russell, C O; Hill, L D; Holmes, III, E R; Hull, D A; Gannon, R; Pope, II, C E

The purpose of this study was to extend existing nuclear medicine techniques for the diagnosis of esophageal motor disorders. A standard homogeneous bolus of 99mtechnetium sulfur colloid in water was swallowed in the supine position under the collimator of a gamma camera linked to a microprocessor. Bolus transit was recorded at 0.4-s intervals, and the movie obtained was used to analyze transit in an objective manner. Ten normal volunteers and 30 subjects with dysphagia not related to mechanical obstruction were studied with this technique. Radionuclide transit studies detected a higher incidence of esophageal motor abnormality than manometry or radiology in the dysphagia group. In addition a definitive description of the functional problem was possible in most cases. Radionuclide transit is a safe noninvasive test and suitable as a screening test for esophageal motor disorders.

• OSTI ID: 5926074
• Journal Information: Gastroenterology; (United States), Vol. 80:5
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
DIGESTIVE SYSTEM DISEASES
DIAGNOSIS
TECHNETIUM 99
DIAGNOSTIC USES
ESOPHAGUS
ISOMERIC NUCLEI
MUSCLES
RADIOCOLLOIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COLLOIDS
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
TECHNETIUM ISOTOPES
USES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques