Participation of free oxygen radicals in damage of porcine erythrocytes
Journal Article
·
· Radiat. Res.; (United States)
Gamma radiation causes disturbances in energy metabolism, decreases in (Na/sup +/-K/sup +/)-ATPase, Mg/sup 2 +/-APTase activity, and increase in the degree of hemolysis in porcine erythrocytes. Our results indicated a contribution of exogenous free radicals in radiation damage to porcine erythrocytes. In the presence of biological and chemical radioprotectors a protective effect with respect to ATPase activity and energy metabolism was observed in the presence of catalase, histidine, glucose, and sulfhydryl compounds. It appears that radiation damage to porcine erythrocytes is due to the action of various radicals formed upon irradiation which react at different rates with various cell constituents.
- Research Organization:
- Univ. of Lodz, Poland
- OSTI ID:
- 5887868
- Journal Information:
- Radiat. Res.; (United States), Vol. 88:1
- Country of Publication:
- United States
- Language:
- English
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OSTI ID:5887868
Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL RADIATION EFFECTS
OXYGEN
ERYTHROCYTES
RADICALS
ATP
ATP-ASE
GAMMA RADIATION
HEMOLYSIS
MAGNESIUM IONS
METABOLISM
POTASSIUM IONS
SODIUM IONS
ACID ANHYDRASES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHARGED PARTICLES
ELECTROMAGNETIC RADIATION
ELEMENTS
ENZYMES
HYDROLASES
IONIZING RADIATIONS
IONS
LYSIS
MATERIALS
NONMETALS
NUCLEOTIDES
ORGANIC COMPOUNDS
PATHOLOGICAL CHANGES
PHOSPHOHYDROLASES
RADIATION EFFECTS
RADIATIONS
560114* - Radiation Effects on Biochemicals- In Animals- (-1987)
BIOLOGICAL RADIATION EFFECTS
OXYGEN
ERYTHROCYTES
RADICALS
ATP
ATP-ASE
GAMMA RADIATION
HEMOLYSIS
MAGNESIUM IONS
METABOLISM
POTASSIUM IONS
SODIUM IONS
ACID ANHYDRASES
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CHARGED PARTICLES
ELECTROMAGNETIC RADIATION
ELEMENTS
ENZYMES
HYDROLASES
IONIZING RADIATIONS
IONS
LYSIS
MATERIALS
NONMETALS
NUCLEOTIDES
ORGANIC COMPOUNDS
PATHOLOGICAL CHANGES
PHOSPHOHYDROLASES
RADIATION EFFECTS
RADIATIONS
560114* - Radiation Effects on Biochemicals- In Animals- (-1987)