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Title: Nephrotoxic mechanisms of drugs and environmental toxins

Book ·
OSTI ID:5858259

This book contains 39 contributions divided into five sections each with its own editor and introductory chapter. The first section of nine chapters is concerned with the pathophysiology of acute renal failure. The second section is concerned with the growing problem of renal failure due to the use of antimicrobial agents such as the aminoglycosides. The various causes of tubulointerstitial nephropathy, notably analgesic drugs and environmental toxins such as mycotoxins and lead, are covered in the third section. Environmental and industrial nephrotoxins, such as cadmium, and halogenated aliphatic hydrocarbons, such as chloroform, are the subject of the fourth section. The last section of nine chapters is concerned mainly with a relatively new area of research into immunological mechanisms of nephrotoxicity and the evidence that drugs and other environmental chemicals can serve as antigens for immune complex formation.

OSTI ID:
5858259
Resource Relation:
Other Information: From review by W.E. Lindup, Intern. J. Environmental Studies; 22: (1984)
Country of Publication:
United States
Language:
English