Quantitative radionuclide angiocardiography for left-to-right cardiac shunts in children
Pulmonary to systemic flow ratios (Qp/Qs) were estimated by quantitative radionuclide angiocardiography (QRAC) in 135 children. The Qp/Qs ratios were derived from pulmonary time/activity curves using a gamma variate model. Eighty-five of these children also had Qp/Qs ratios estimated by oximetry at cardiac catheterization. The correlation between Qp/Qs, determined by QRAC and by oximetry was good. This relatively noninvasive technique has now been used to estimate the Qp/Qs ratio in 34 children with a clinically suspected left-to-right shunt, and postoperatively in 16 cases with residual murmurs; it has obviated the need for catheterization in many of these patients. The technique may also be used serially to determine changes in the Qp/Qs ratio in patients with known left-to-right shunts.
- Research Organization:
- Adelaide Children's Hospital, North Adelaide, Australia
- OSTI ID:
- 5855902
- Journal Information:
- Pediatr. Cardiol.; (United States), Vol. 3:1
- Country of Publication:
- United States
- Language:
- English
Similar Records
Noninvasive detection and quantification of left-to-right shunts in children using oxygen-15 labeled carbon dioxide
Radionuclide quantitation of left-to-right cardiac shunts using deconvolution analysis: concise communication. [Tc-99m]
Related Subjects
BLOOD FLOW
RADIOCARDIOGRAPHY
CARDIOVASCULAR DISEASES
DIAGNOSIS
CONGENITAL MALFORMATIONS
CHILDREN
HEART
RADIOISOTOPES
AGE GROUPS
BODY
CARDIOGRAPHY
CARDIOVASCULAR SYSTEM
DIAGNOSTIC TECHNIQUES
DISEASES
ISOTOPES
MALFORMATIONS
ORGANS
PATHOLOGICAL CHANGES
550601* - Medicine- Unsealed Radionuclides in Diagnostics