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Title: Octanol-water partition coefficients of substituted alpha, N-diphenylnitrones and benzonitrile N-oxides

Journal Article · · J. Pharm. Sci.; (United States)

Experimental octanol-water partition coefficients are reported for substituted alpha, N-diphenylnitrones and benzonitrile N-oxides. The results of these measurements are used to calculate the aromatic fragment constants pi HC = N(O)C6H5, pi C = N----O, fHC = N(O), and fC = N----O for the group contribution methods of Hansch and Leo.

Research Organization:
Kent State Univ., OH
OSTI ID:
5811100
Journal Information:
J. Pharm. Sci.; (United States), Vol. 10
Country of Publication:
United States
Language:
English