New techniques for positron emission tomography in the study of human neurological disorders
We continue our focus to develop more cost effective and efficient means for producing new functionally specific tracers and more simple, less expensive, means for acquiring and interpreting quantitative data. These improved processes are required for the future growth of positron emission tomography (PET) as a sophisticated research meeting and for the transfer of this technology to clinical use. Our approach concentrates on two separate yet related areas, radiosynthesis and data analysis. The program is divided into four subprojects, the first pair related to radiosynthesis, and the second pair related to data analysis. Progress during the past project year has been excellent in both accomplishment and publication record. 26 refs.
- Research Organization:
- Michigan Univ., Ann Arbor, MI (USA). School of Medicine
- Sponsoring Organization:
- USDOE; USDOE, Washington, DC (USA)
- DOE Contract Number:
- FG02-87ER60561
- OSTI ID:
- 5735676
- Report Number(s):
- DOE/ER/60561-5; ON: DE91013855
- Country of Publication:
- United States
- Language:
- English
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New techniques for positron emission tomography in the study of human neurological disorders
New techniques for positron emission tomography in the study of human neurological disorders. Progress report, June 1990--June 1993
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38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
BRAIN
POSITRON COMPUTED TOMOGRAPHY
LIGANDS
LABELLING
METABOLITES
RADIONUCLIDE KINETICS
MATHEMATICAL MODELS
RADIOPHARMACEUTICALS
PRODUCTION
ALGORITHMS
CARBON 11
COMPUTERIZED SIMULATION
DIGITAL FILTERS
FLUORINE 18
MAN
NERVOUS SYSTEM DISEASES
NEUROREGULATORS
OXYGEN 15
PARAMETRIC ANALYSIS
PROGRESS REPORT
RADIOCHEMISTRY
SENSITIVITY ANALYSIS
SYMPATHOMIMETICS
THREE-DIMENSIONAL CALCULATIONS
TISSUE DISTRIBUTION
TRACER TECHNIQUES
ANIMALS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
BODY
CARBON ISOTOPES
CENTRAL NERVOUS SYSTEM
CHEMISTRY
COMPUTERIZED TOMOGRAPHY
DIAGNOSTIC TECHNIQUES
DISEASES
DISTRIBUTION
DOCUMENT TYPES
DRUGS
EMISSION COMPUTED TOMOGRAPHY
EVEN-ODD NUCLEI
FLUORINE ISOTOPES
HOURS LIVING RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MAMMALS
MATHEMATICAL LOGIC
MINUTES LIVING RADIOISOTOPES
NANOSEC LIVING RADIOISOTOPES
NERVOUS SYSTEM
NUCLEI
ODD-ODD NUCLEI
ORGANS
OXYGEN ISOTOPES
PRIMATES
RADIOISOTOPES
SIMULATION
TOMOGRAPHY
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
400703 - Radiochemistry & Nuclear Chemistry- Radioisotope Production