Studies on acute in vivo exposure of rats to 2450-MHz Microwave Radiation. Part II. Effects on thyroid and adrenal axes hormones
The effects of 8 hr continuous exposure of rats to 2450-MHz (cw) microwave radiation were studied at incident power densities of 0, 2 and 10 mW/cm/sup 2/. Thyroid axis function, as measured by serum thyroxine (T/sub 4/) and triiodothyronine (T/sub 3/) as well as T/sub 3/ uptake, free thyroxine index, and adjusted-T/sub 4/ values was not altered by the experimental conditions. Adrenal axis activity was also unaffected in rats exposed to 2 mW/cm/sup 2/ microwave radiation for 8 hr. In the 10 mW/cm/sup 2/ group, the serum corticosterone levels were less than in the 0 or 2 mW/cm/sup 2/ groups (7.8 versus 9.9 ..mu..g/dl). The experimental protocol increased serum corticosterone levels (7.0 versus 9.9 ..mu..g/dl for the nonhandled and sham-exposed groups, respectively); however, the corticosterone concentration in the 10 mW/cm/sup 2/ group was similar to that in the untreated (nonhandled) controls (7.8 versus 7.0 ..mu..g/dl). This modified adrenal axis function gives further support to the concept that microwave radiation affects endocrine function.
- Research Organization:
- National Inst. of Environmental Health Sciences, Research Triangle Part, NC
- OSTI ID:
- 5627099
- Journal Information:
- Radiat. Res.; (United States), Vol. 88:3
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
MICROWAVE RADIATION
BIOLOGICAL EFFECTS
ADRENAL GLANDS
CORTICOSTEROIDS
RATS
THYROID
THYRONINE
THYROXINE
ADRENAL HORMONES
AMINO ACIDS
ANIMALS
BODY
CARBOXYLIC ACIDS
ELECTROMAGNETIC RADIATION
ENDOCRINE GLANDS
GLANDS
HORMONES
HYDROXY ACIDS
HYDROXY COMPOUNDS
KETONES
MAMMALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC IODINE COMPOUNDS
ORGANS
PEPTIDE HORMONES
PREGNANES
RADIATIONS
RODENTS
STEROID HORMONES
STEROIDS
THYROID HORMONES
VERTEBRATES
560400* - Other Environmental Pollutant Effects