Acute metal toxicology of olfaction in coho salmon: behavior, receptors, and odor-metal complexation

Journal Article · Tue Apr 01 00:00:00 EST 1986 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01623554· OSTI ID:5524074

Rehnberg, B C; Schreck, C B

The objective of this research was to determine the acute toxicities of mercury (Hg), copper (Cu), and zinc (Zn) to coho salmon olfaction. The authors used a behavioral assay of olfaction based on an avoidance reaction to L-serine in a two-choice Y-trough. A second objective was to gain some understanding of the mechanism of metal-induced olfactory inhibition by observing how metals affect the binding of L-serine to its olfactory cell membrane receptor. They have also taken the novel approach of addressing olfactory toxicology from the perspective of the odor molecule by considering metal speciation and metal-serpine complexation chemistry on the basis of chemical equilibrium computations.

• Research Organization: Oregon State Univ., Corvallis
• OSTI ID: 5524074
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Vol. 36:4
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
COPPER COMPOUNDS
TOXICITY
MERCURY COMPOUNDS
OLFACTORY BULBS
INHIBITION
ZINC COMPOUNDS
AVOIDANCE
CHEMORECEPTORS
ODOR
SALMON
SERINE
AMINO ACIDS
ANADROMOUS FISHES
ANIMALS
AQUATIC ORGANISMS
BEHAVIOR
BODY
BRAIN
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
FISHES
HYDROXY ACIDS
NERVOUS SYSTEM
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANOLEPTIC PROPERTIES
ORGANS
TRANSITION ELEMENT COMPOUNDS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)