Commercial production of radioisotopes for nuclear medicine, 1970-1980
The first small cyclotrons were installed for commercial production of radioisotopes at New England Nuclear Corporation, Billerica, Massachusetts, and at Medi-Physics, Emeryville, California. Both machines were Cyclotron Corporation Cs-22 multiple particle, fixed energy cyclotrons. In the ten years that followed, the total number of commercial radioisotope producing small accelerators has grown to ten, with four more projected for 1981. The beam energy requirement for the first accelerators was modest; 22 MeV protons, 12 MeV deuterons, 24 MeV He-4, and 31 MeV He-3; and commercial radioisotope production for nuclear medicine utilized all four particles. The first product available from cyclotron production was fluorine-18 from the /sup 16/O(/sup 3/He, p)/sup 18/F reaction. Injected intravenously as no-carrier-added Na/sup 18/F, the radionuclide quickly concentrated in bone, providing the nuclear medicine physician with diagnostic information on skeletal abnormalities including metastatic bone disease.
- Research Organization:
- Medi-Physics, Inc., Emeryville, CA
- OSTI ID:
- 5477908
- Report Number(s):
- CONF-801111-
- Journal Information:
- IEEE Trans. Nucl. Sci.; (United States), Vol. NS-28:2; Conference: 6. conference on application of accelerators in research and industry, Denton, TX, USA, 3 Nov 1980
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
43 PARTICLE ACCELERATORS
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
CYCLOTRONS
RADIOISOTOPES
NUCLEAR MEDICINE
PRODUCTION
COMMERCIALIZATION
FLUORINE 18
GALLIUM 67
INDIUM 111
IODINE 123
POTASSIUM 43
RADIOPHARMACEUTICALS
RUBIDIUM 81
THALLIUM 201
ACCELERATORS
ALKALI METAL ISOTOPES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CYCLIC ACCELERATORS
DAYS LIVING RADIOISOTOPES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
FLUORINE ISOTOPES
GALLIUM ISOTOPES
HEAVY NUCLEI
HOURS LIVING RADIOISOTOPES
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LIGHT NUCLEI
MEDICINE
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ODD-ODD NUCLEI
POTASSIUM ISOTOPES
RUBIDIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
430303 - Particle Accelerators- Experimental Facilities & Equipment
400703 - Radiochemistry & Nuclear Chemistry- Radioisotope Production