Overview of the current attempts toward the medical treatment of cataract
A variety of agents are currently available that claim to either prevent, delay, or reverse cataracts associated with aging (senile cataracts), radiation, or diabetes and galactosemia (sugar cataracts). Senile cataract therapy includes formulation containing inorganic salts, nutritional supplements, natural product extracts, sulfhydryl, and sulfonic acid containing compounds and miscellaneous redox and nonsteroidal anti-inflammatory compounds. Agents associated with the treatment of radiation cataracts include antioxidants and free radial scavengers. Aldose reductase inhibitors have been effective in the prevention of sugar cataracts. A summary of these agents and their potential ocular effects are presented.
- Research Organization:
- Laboratory of Vision Research, National Eye Institute, Bethesda, Maryland
- OSTI ID:
- 5475950
- Journal Information:
- Ophthalmology (Rochester, Minn.); (United States), Vol. 90:4
- Country of Publication:
- United States
- Language:
- English
Similar Records
Aldose reductase mediates retinal microglia activation
Promoter demethylation of Keap1 gene in human diabetic cataractous lenses
Related Subjects
ANTIPYRETICS
BIOLOGICAL EFFECTS
CATARACTS
RADIOINDUCTION
THERAPY
CORNEA
BIOLOGICAL RADIATION EFFECTS
DIABETES MELLITUS
SIDE EFFECTS
SULFONIC ACIDS
THIOLS
ENZYME ACTIVITY
NUTRITION
OXIDOREDUCTASES
BODY
BODY AREAS
CENTRAL NERVOUS SYSTEM DEPRESSANTS
DISEASES
DRUGS
ENDOCRINE DISEASES
ENZYMES
EYES
FACE
HEAD
METABOLIC DISEASES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
RADIATION EFFECTS
SENSE ORGANS
SENSE ORGANS DISEASES
560151* - Radiation Effects on Animals- Man