Transmission computed tomography, Tc-99m MAA scintigraphy, and plain chest radiography after experimentally produced acute pulmonary arterial occlusion in the dog

Journal Article · Sat Dec 01 00:00:00 EST 1979 · J. Nucl. Med.; (United States)

OSTI ID:5437004

Grossman, Z D; Gagne, G; Zens, A; Thomas, F D; Chamberlain, C C; Singh, A; Cohen, W N; Heitzman, E R

We have occluded segmental and subsegmental pulmonary arteries in the dog with Swan-Ganz balloon catheters or i.v. injection of autologous clot, and have studied the chest with transmission computed tomography (TCT), Tc-99m-MAA gamma imaging, and plain radiographs. The arterial occlusions were between 1 and 5 hr old at the time of imaging. Radiographs revealed no lesions. Tc-99m MAA scans revealed ten of 11 lesions. When a TCT image was made before i.v. injection of Renografin-60, two of 11 lesions were identified; after Renografin the score was four out of ten. The appearance of lesions on TCT was highly variable. Tc-99m-MAA gamma imaging, therefore, is far more accurate than TCT in the identification of small experimentally produced acute pulmonary arterial occlusions in the dog, and our study fails to suggest a secure place for TCT in the diagnosis of small, acute human pulmonary emboli. The commonly-held assumption held postembolic lung is oligemic is questioned.

• Research Organization: State Univ. of New York, Syracuse
• OSTI ID: 5437004
• Journal Information: J. Nucl. Med.; (United States), Vol. 20:12
• Country of Publication: United States
• Language: English

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