Quantitative bone and 67Ga scintigraphy in the differentiation of necrotizing external otitis from severe external otitis

Journal Article · Sat Jun 01 00:00:00 EDT 1991 · Archives of Otolaryngology, Head and Neck Surgery; (United States)

DOI:https://doi.org/10.1001/archotol.1991.01870180059012· OSTI ID:5397869

Uri, N; Gips, S; Front, A; Meyer, S W; Hardoff, R ^[1]

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1. Department of Otolaryngology, Lady Davis Carmel Hospital, Haifa (Israel)

Qualitative technetium Tc 99m bone scintigraphy using phosphate compounds and gallium 67 scintigraphy were described as a helpful means in diagnosing necrotizing external otitis (NEO). They were, however, claimed to be nonspecific. Quantitative Tc 99m methylene diphosphonate bone scintigraphy and gallium 67 scintigraphy were performed in eight patients with NEO and in 20 patients with severe external otitis, in order to prove usefulness of scintigraphy in the diagnosis of NEO. Ratios of lesion to nonlesion for bone scintigraphy were 1.67 {plus minus} 0.16 in patients with NEO and 1.08 {plus minus} 0.09 in patients with severe external otitis, and for gallium 67 scintigraphy they were 1.35 {plus minus} 0.24 in NEO patients and 1.05 {plus minus} 0.03 in patients with severe external otitis. There was no difference in uptake between diabetic patients with severe external otitis and nondiabetic patients. The scintigraphic studies were also evaluated using a qualitative scoring method (scores 0 to +4), according to the intensity of the radiopharmaceutical uptake. This method was found to be inferior in the diagnosis of NEO compared with the quantitative method. We conclude that lesion-to-nonlesion ratios greater than 1.5 and 1.3 on bone and gallium 67 scintigraphy, respectively, are indicative of NEO. Quantitative bone scintigraphy, which is quicker to perform, may be used as a single imaging modality for the diagnosis of NEO.

• OSTI ID: 5397869
• Journal Information: Archives of Otolaryngology, Head and Neck Surgery; (United States), Vol. 117:6; ISSN 0886-4470
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
SENSE ORGANS DISEASES
DIAGNOSIS
SKELETON
SCINTISCANNING
AUDITORY ORGANS
DIABETES MELLITUS
GALLIUM 67
ISOMERIC NUCLEI
NECROSIS
PATIENTS
TECHNETIUM 99
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
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DIAGNOSTIC TECHNIQUES
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ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE DISEASES
GALLIUM ISOTOPES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
METABOLIC DISEASES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATHOLOGICAL CHANGES
RADIOISOTOPE SCANNING
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SENSE ORGANS
TECHNETIUM ISOTOPES
YEARS LIVING RADIOI
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