Gated right ventricular studies using krypton-81m: comparison with first-pass studies using gold-195m
Krypton-81m, given by continuous i.v. infusion, has been successfully used for the equilibrium ECG-gated assessment of right ventricular function. We compared gated studies with 81mKr (half-life 13 sec) with first-pass studies using 195mAu (half-life 30.5 sec). Krypton studies analyzed using variable regions of interest (ROIs) led to a significantly higher calculated right ventricular ejection fraction (RVEF) than with a fixed ROI, both with and without background correction. The differences between first-pass studies and gated studies without background correction were significant (p less than 0.01), whereas they were not with background correction. These data suggest that large systematic errors exist in the calculation of RVEF depending on the analysis method and that background correction is important when different techniques are compared.
- Research Organization:
- St. Bartholomew's Hospital, London, England
- OSTI ID:
- 5330419
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 5
- Country of Publication:
- United States
- Language:
- English
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HEART
RADIOISOTOPE SCANNING
KRYPTON 81
DIAGNOSTIC USES
COMPARATIVE EVALUATIONS
ERRORS
GOLD 195
BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
GOLD ISOTOPES
HEAVY NUCLEI
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KRYPTON ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
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SECONDS LIVING RADIOISOTOPES
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550601* - Medicine- Unsealed Radionuclides in Diagnostics