THE EFFECT OF 5.3-Mev POLONIUM-210 ALPHA PARTICLES ON THE ELECTRICAL ACTIVITY OF /cap alpha/- AND /cap beta/-FIBERS OF THE FROG SCIATIC NERVE
Nerve bundles were excised from the sciatic nerves of decerebrated Rana temporaria, and tested by electrical stimulation to obtain a compound spike configuration, which indicated the presence of alpha - and BETA -fibers. A typical experiment with a bundle of 5 intact fibers, irradiated with a dose of 6000 rep (1200 rep/min) showed an alpha -potential decrease of st run. Concent 50% 20 min alter irradiation. The initial decrease of the action potential due to irradiation was observed especially with irradiation doses smaller than 6000 rep. However, this increase in the action potential had a different time course for the alpha - and the BETA -elevation of the compound potential. The BETA - potential increased slightly during the first 2 min, whereas no detectable change in the alpha -potential was noted. The results indicate that the alpha and BETA -fibers of the sciatic nerve of the frog show a different response to irradiation with heavy particles. The BETA fibers seem to be more sensitive to irradiation in that the enhancement of the BETA -potential appeared earlier than the enhancement of the alpha -potential. (TCO)
- Research Organization:
- Univ. of Helsinki, Finland
- NSA Number:
- NSA-17-021483
- OSTI ID:
- 4719028
- Journal Information:
- Ann. Med. Exptl. Biol. Fenniae (Helsinki), Vol. Vol: 39; Other Information: Orig. Receipt Date: 31-DEC-63
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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