CHEMICAL SYNTHESIS OF TRITIUM-LABELED LINOLEIC ACID
Tritium-labeled linoleic acid with a specific activity of 357 mC/mmole was obtained in 70% yield from totally synthesized octadeca-9,12-diynoic acid. A source of 1 curie of tritium gas was used to semihydrogenate the diacetylenic acid in the presence of Lindlar's catalyst. Chemical and radiochemical purity of the final product were assessed by chromatographic methods. Evidence from mild oxidation indicated that the tritium-labeled linoleic acid was prepared with a specificity of greater than 95% of the activity at the
- Research Organization:
- Univ. of Illinois, Urbana
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-18-016070
- OSTI ID:
- 4067997
- Journal Information:
- Biochemistry (U.S.), Vol. Vol: 3; Other Information: Orig. Receipt Date: 31-DEC-64
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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