Confocal acoustic radiation force optical coherence elastography using a ring ultrasonic transducer

Journal Article · Mon Mar 24 00:00:00 EDT 2014 · Applied Physics Letters

DOI:https://doi.org/10.1063/1.4869562· OSTI ID:22258593

Qi, Wenjuan ^[1]; Li, Rui ^[1]; Ma, Teng; Kirk Shung, K.; Zhou, Qifa ^[2]; Chen, Zhongping ^[1]

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1. Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road East, Irvine, California 92612 (United States)
2. Department of Biomedical Engineering, NIH Ultrasonic Transducer Resource Center, University of Southern California, Los Angeles, California 90089 (United States)

We designed and developed a confocal acoustic radiation force optical coherence elastography system. A ring ultrasound transducer was used to achieve reflection mode excitation and generate an oscillating acoustic radiation force in order to generate displacements within the tissue, which were detected using the phase-resolved optical coherence elastography method. Both phantom and human tissue tests indicate that this system is able to sense the stiffness difference of samples and quantitatively map the elastic property of materials. Our confocal setup promises a great potential for point by point elastic imaging in vivo and differentiation of diseased tissues from normal tissue.

• OSTI ID: 22258593
• Journal Information: Applied Physics Letters, Vol. 104, Issue 12; Other Information: (c) 2014 AIP Publishing LLC; Country of input: International Atomic Energy Agency (IAEA); ISSN 0003-6951
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ACOUSTIC DETECTION
ACOUSTICS
ELASTICITY
PHANTOMS
RINGS
TRANSDUCERS
ULTRASONOGRAPHY