Pelvic Normal Tissue Contouring Guidelines for Radiation Therapy: A Radiation Therapy Oncology Group Consensus Panel Atlas
- Commonwealth Hematology and Oncology, Weymouth, MA (United States)
- Radiation Therapy Oncology Group, Philadelphia, PA (United States)
- Washington University School of Medicine, St Louis, MO (United States)
- Department of Radiation Oncology, McGill University Health Center, Montreal, Quebec (Canada)
- Radiation Oncology Centers, Radiological Associates of Sacramento, Sacramento, CA (United States)
- Department of Radiation Oncology, Medical College of Wisconsin, Milwaukee, WI (United States)
- Department of Radiation Oncology, Duke University Medical Center, Durham, NC (United States)
- Cedars-Sinai Medical Center, Los Angeles, CA (United States)
- Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA (United States)
- Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario (Canada)
- Department of Radiation Oncology, Boston Medical Center, Boston University School of Medicine, Boston, MA (United States)
- Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX (United States)
- University of Miami, Miami, FL (United States)
Purpose: To define a male and female pelvic normal tissue contouring atlas for Radiation Therapy Oncology Group (RTOG) trials. Methods and Materials: One male pelvis computed tomography (CT) data set and one female pelvis CT data set were shared via the Image-Guided Therapy QA Center. A total of 16 radiation oncologists participated. The following organs at risk were contoured in both CT sets: anus, anorectum, rectum (gastrointestinal and genitourinary definitions), bowel NOS (not otherwise specified), small bowel, large bowel, and proximal femurs. The following were contoured in the male set only: bladder, prostate, seminal vesicles, and penile bulb. The following were contoured in the female set only: uterus, cervix, and ovaries. A computer program used the binomial distribution to generate 95% group consensus contours. These contours and definitions were then reviewed by the group and modified. Results: The panel achieved consensus definitions for pelvic normal tissue contouring in RTOG trials with these standardized names: Rectum, AnoRectum, SmallBowel, Colon, BowelBag, Bladder, UteroCervix, Adnexa{sub R}, Adnexa{sub L}, Prostate, SeminalVesc, PenileBulb, Femur{sub R}, and Femur{sub L}. Two additional normal structures whose purpose is to serve as targets in anal and rectal cancer were defined: AnoRectumSig and Mesorectum. Detailed target volume contouring guidelines and images are discussed. Conclusions: Consensus guidelines for pelvic normal tissue contouring were reached and are available as a CT image atlas on the RTOG Web site. This will allow uniformity in defining normal tissues for clinical trials delivering pelvic radiation and will facilitate future normal tissue complication research.
- OSTI ID:
- 22058908
- Journal Information:
- International Journal of Radiation Oncology, Biology and Physics, Vol. 83, Issue 3; Other Information: Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0360-3016
- Country of Publication:
- United States
- Language:
- English
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