SIBYLS - a SAXS and Protein Crystallography Beamline at the ALS

Journal Article · Wed May 12 00:00:00 EDT 2004 · AIP Conference Proceedings

DOI:https://doi.org/10.1063/1.1757844· OSTI ID:20652993

Trame, C; MacDowell, A A; Celestre, R S; Padmore, H A; Cambie, D; Domning, E E; Duarte, R M; Kelez, N; Plate, D W; Holton, J M; Frankel, K; Tsutakawa, S; Cooper, P K ^[1]; Tsuruta, H ^[2]; Tainer, J A ^[1]

---

1. Lawrence Berkeley National Lab., 1 Cyclotron Road, Berkeley, CA 94720 (United States)
2. Stanford Synchrotron Radiation Lab., 2575 Sand Hill Road, Menlo Park, California, 94025 (United States)

The new Structurally Integrated BiologY for Life Sciences (SIBYLS) beamline at the Advanced Light Source will be dedicated to Macromolecular Crystallography (PX) and Small Angle X-ray Scattering (SAXS). SAXS will provide structural information of macromolecules in solutions and will complement high resolution PX studies on the same systems but in a crystalline state. The x-ray source is one of the 5 Tesla superbend dipoles recently installed at the ALS that allows for a hard x-ray program to be developed on the relatively low energy Advanced Light Source (ALS) ring (1.9 GeV). The beamline is equipped with fast interchangeable monochromator elements, consisting of either a pair of single Si(111) crystals for crystallography, or a pair of multilayers for the SAXS mode data collection (E/{delta}E{approx}1/110). Flux rates with Si(111) crystals for PX are measured as 2x1011 hv/sec through a 100{mu}m pinhole at 12.4KeV. For SAXS the flux is up to 3x1013photons/sec at 10KeV with all apertures open when using the multilayer monochromator elements. The performance characteristics of this unique beamline will be described.

• OSTI ID: 20652993
• Journal Information: AIP Conference Proceedings, Vol. 705, Issue 1; Conference: 8. international conference on synchrotron radiation instrumentation, San Francisco, CA (United States), 25-29 Aug 2003; Other Information: DOI: 10.1063/1.1757844; (c) 2004 American Institute of Physics; Country of input: International Atomic Energy Agency (IAEA); ISSN 0094-243X
• Country of Publication: United States
• Language: English

Related Subjects

43 PARTICLE ACCELERATORS
ADVANCED LIGHT SOURCE
APERTURES
BEAM OPTICS
CRYSTALLOGRAPHY
CRYSTALS
DIPOLES
ELECTRON BEAMS
GEV RANGE 01-10
HARD X RADIATION
PROTEINS
RESOLUTION
SILICON
SMALL ANGLE SCATTERING
SOLUTIONS
SYNCHROTRON RADIATION
X-RAY DIFFRACTION
X-RAY SOURCES