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Title: Method for improved selectivity in photo-activation of molecular agents

Patent ·
OSTI ID:20013251

This application describes a method for the treatment of a particular volume of plant or animal tissue comprising the steps of treating the tissue with at least one photo-active molecular agent. In this treatment the tissue retains at least a portion of one photo-active molecular agent. Then the tissue is treated with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent, causing it to become active in the plant or animal tissue. There is also disclosed a method for the treatment of cancer in plant or animal tissue and a method for producing at least one photo-activated molecular agent in a particular volume of a material.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-84OR21400
Assignee:
ORNL; EDB-00:006673
Application Number:
Int. Cl. C07H 21/64; C07K 5/00; C07K 14/00; A61B 19/00; US 5,998,597/A/; 8-989,231; TRN: IM200010%%119
OSTI ID:
20013251
Resource Relation:
Other Information: PBD: 7 Dec 1999
Country of Publication:
United States
Language:
English