PXR: More Than Just a Master Xenobiotic Receptor
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November 2017 |
The Dietary Isothiocyanate Sulforaphane Is an Antagonist of the Human Steroid and Xenobiotic Nuclear Receptor
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October 2006 |
Overview of the CCP 4 suite and current developments
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March 2011 |
The vitamin E derivative garcinoic acid from Garcinia kola nut seeds attenuates the inflammatory response
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June 2019 |
PXR antagonists and implication in drug metabolism
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January 2013 |
The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism
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October 2002 |
Rifaximin for the Treatment of Hepatic Encephalopathy
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August 2008 |
Pregnane X receptor activation ameliorates DSS-induced inflammatory bowel disease via inhibition of NF-κB target gene expression
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April 2007 |
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
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August 2014 |
Increased plasma levels of the lipoperoxyl radical-derived vitamin E metabolite α-tocopheryl quinone are an early indicator of lipotoxicity in fatty liver subjects
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February 2019 |
An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway
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January 1998 |
Review article: the potential mechanisms of action of rifaximin in the management of inflammatory bowel diseases
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November 2015 |
Selective Agonism of Human Pregnane X Receptor by Individual Ginkgolides
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March 2012 |
Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability
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May 2008 |
Vitamin E: Emerging aspects and new directions
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January 2017 |
a-13'-OH is the main product of a-tocopherol metabolism and influences CYP4F2 and PPAR? gene expression in HepG2 human hepatocarcinoma cells
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July 2016 |
Long-Chain Metabolites of Vitamin E: Metabolic Activation as a General Concept for Lipid-Soluble Vitamins?
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January 2018 |
Proapoptotic effects of long-chain vitamin E metabolites in HepG2 cells are mediated by oxidative stress
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November 2010 |
The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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December 1999 |
SXR, a novel steroid and xenobioticsensing nuclear receptor
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October 1998 |
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
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December 2013 |
Alleviation of Gut Inflammation by Cdx2/Pxr Pathway in a Mouse Model of Chemical Colitis
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July 2012 |
Structural and Functional Analysis of the Human Nuclear Xenobiotic Receptor PXR in Complex with RXRα
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July 2013 |
Nuclear Receptors CAR and PXR; therapeutic targets for cholestatic liver disease
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January 2011 |
CYP4F2 repression and a modified alpha-tocopherol (vitamin E) metabolism are two independent consequences of ethanol toxicity in human hepatocytes
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April 2017 |
Targeting xenobiotic receptors PXR and CAR for metabolic diseases
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October 2012 |
Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
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February 2009 |
Therapy for and Prevention of Traveler's Diarrhea
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July 2007 |
Nuclear Receptors in Nonalcoholic Fatty Liver Disease
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January 2012 |
Crystal structure of the PXR–T1317 complex provides a scaffold to examine the potential for receptor antagonism
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March 2007 |
Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
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July 2010 |
PXR as a mediator of herb–drug interaction
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April 2018 |
Conventional cell culture media do not adequately supply cells with antioxidants and thus facilitate peroxide-induced genotoxicity
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January 1996 |
Glutathione S-transferase pi expression regulates the Nrf2-dependent response to hormetic diselenides
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November 2015 |
The long chain α-tocopherol metabolite α-13’-COOH and γ-tocotrienol induce P-glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180
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November 2016 |
Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor
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September 2013 |
Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters
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April 2012 |
Tocopherols are metabolized in HepG2 cells by side chain ω-oxidation and consecutive β-oxidation
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July 2001 |
Constituents of the Seeds of Garcinia kola : Two New Antioxidants, Garcinoic Acid and Garcinal
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January 1997 |
Vitamin E activates gene expression via the pregnane X receptor
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January 2003 |
Interactions of Polyphenolic Compounds with Drug Disposition and Metabolism
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December 2007 |
Pregnane X receptor as a target for treatment of inflammatory bowel disorders
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June 2012 |
HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity †
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March 2000 |
Overcoming Roadblocks in Lead Optimization: A Thermodynamic Perspective
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January 2006 |
Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase
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September 2018 |
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
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December 1983 |
Nutritional and lipidomics biomarkers of docosahexaenoic acid-based multivitamin therapy in pediatric NASH
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February 2019 |
Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes
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September 2016 |
Nuclear receptors and nonalcoholic fatty liver disease
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September 2016 |
Identities and Differences in the Metabolism of Tocotrienols and Tocopherols in HepG2 Cells
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October 2002 |
Powerful antioxidative agents based on garcinoic acid from Garcinia kola
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May 2002 |
Configuration of the vitamin E analogue garcinoic acid extracted from garcinia kola seeds
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May 2009 |
Unveiling a New Essential Cis Element for the Transactivation of the CYP3A4 Gene by Xenobiotics
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December 2008 |
Glucuronidation of bile acids under flow conditions: design of experiments and Koenigs–Knorr reaction optimization
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January 2014 |
Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
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January 2014 |