Activation of natural killer cells with interleukin 2 (IL-2) and IL-12 increases perforin binding and subsequent lysis of tumour cells: Activation With IL-2 and IL-12 Increases Perforin Binding
|
journal
|
September 2001 |
Preactivation with IL-12, IL-15, and IL-18 Induces CD25 and a Functional High-Affinity IL-2 Receptor on Human Cytokine-Induced Memory-like Natural Killer Cells
|
journal
|
April 2014 |
The interleukin-12 subunit p40 specifically inhibits effects of the interleukin-12 heterodimer
|
journal
|
September 1993 |
IL-12 family cytokines: immunological playmakers
|
journal
|
July 2012 |
A Human IgSF Cell-Surface Interactome Reveals a Complex Network of Protein-Protein Interactions
|
journal
|
August 2020 |
Revisiting Interleukin-12 as a Cancer Immunotherapy Agent
|
journal
|
March 2018 |
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
|
journal
|
March 2010 |
Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line
|
journal
|
October 2002 |
Molecular Mechanisms of IFN-γ to Up-Regulate MHC Class I Antigen Processing and Presentation
|
journal
|
January 2009 |
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8+ T cells
|
journal
|
February 2015 |
T cell receptor antagonist peptides induce positive selection
|
journal
|
January 1994 |
Antitumor and antimetastatic activity of interleukin 12 against murine tumors.
|
journal
|
October 1993 |
Charged residues dominate a unique interlocking topography in the heterodimeric cytokine interleukin-12
|
journal
|
July 2000 |
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rβ1
|
journal
|
January 2018 |
Anti-CD47 antibody-mediated phagocytosis of cancer by macrophages primes an effective antitumor T-cell response
|
journal
|
May 2013 |
Structural Biology of Shared Cytokine Receptors
|
journal
|
April 2009 |
Isolating and engineering human antibodies using yeast surface display
|
journal
|
July 2006 |
Collaboration gets the most out of software
|
journal
|
September 2013 |
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.
|
journal
|
September 1989 |
Cytokine activation induces human memory-like NK cells
|
journal
|
December 2012 |
Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells
|
journal
|
March 1997 |
Therapeutic targeting of the IL-12/23 pathways: generation and characterization of ustekinumab
|
journal
|
July 2011 |
Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12
|
journal
|
November 2000 |
Structural Basis for the Dual Recognition of IL-12 and IL-23 by Ustekinumab
|
journal
|
October 2010 |
IL-12p35 induces expansion of IL-10 and IL-35-expressing regulatory B cells and ameliorates autoimmune disease
|
journal
|
September 2017 |
Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
|
journal
|
October 2019 |
A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R
|
journal
|
June 2002 |
Direct Interaction of STAT4 with the IL-12 Receptor
|
journal
|
August 1999 |
Cooperation of Natural Killer Cell Stimulatory Factor/Interleukin-12 with Other Stimuli in the Induction of Cytokines and Cytotoxic Cell-Associated Molecules in Human T and NK Cells
|
journal
|
July 1994 |
Structure of an Extracellular gp130 Cytokine Receptor Signaling Complex
|
journal
|
March 2001 |
Site-Specific Biotinylation of Purified Proteins Using BirA
|
book
|
December 2014 |
Treatment of disseminated ovarian cancer using nonviral interleukin-12 gene therapy delivered intraperitoneally
|
journal
|
August 2009 |
Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine–Nanobody Complex
|
journal
|
August 2017 |
IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells
|
journal
|
June 2002 |
CTFFIND4: Fast and accurate defocus estimation from electron micrographs
|
journal
|
November 2015 |
A novel IL-23p19/Ebi3 (IL-39) cytokine mediates inflammation in Lupus-like mice: Molecular immunology
|
journal
|
April 2016 |
An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor
|
journal
|
July 2007 |
The JAK-STAT Signaling Pathway: Input and Output Integration
|
journal
|
February 2007 |
Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells
|
journal
|
April 2013 |
New tools for automated high-resolution cryo-EM structure determination in RELION-3
|
journal
|
November 2018 |
IL-12 and IL-7 synergize to control mucosal-associated invariant T-cell cytotoxic responses to bacterial infection
|
journal
|
June 2018 |
MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
|
journal
|
February 2017 |
IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12Rβ1 internalization and suppress EAE
|
journal
|
August 2020 |
XDS
|
journal
|
January 2010 |
Inference of Macromolecular Assemblies from Crystalline State
|
journal
|
September 2007 |
Tissue-based map of the human proteome
|
journal
|
January 2015 |
IL-21 induces IL-22 production in CD4+ T cells
|
journal
|
May 2014 |
Clinical Trials: IL-12 Deaths: Explanation and a Puzzle
|
journal
|
November 1995 |
Gctf: Real-time CTF determination and correction
|
journal
|
January 2016 |
Administration of two macrophage-derived interferon-γ-inducing factors (IL-12 and IL-15) induces a lethal systemic inflammatory response in mice that is dependent on natural killer cells but does not require interferon-γ
|
journal
|
March 2002 |
Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy
|
journal
|
June 2019 |
IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level
|
journal
|
February 2017 |
The composition and signaling of the IL-35 receptor are unconventional
|
journal
|
February 2012 |
The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel
|
journal
|
June 2012 |
Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody
|
journal
|
October 2004 |
Non-Canonical Interleukin 23 Receptor Complex Assembly
|
journal
|
January 2015 |
The Lipid Binding Pleckstrin Homology Domain in UNC-104 Kinesin is Necessary for Synaptic Vesicle Transport in Caenorhabditis elegans
|
journal
|
August 2004 |
The Structure of Interleukin-23 Reveals the Molecular Basis of p40 Subunit Sharing with Interleukin-12
|
journal
|
October 2008 |
IL-23 Receptor Expression on γδ T Cells Correlates with Their Enhancing or Suppressive Effects on Autoreactive T Cells in Experimental Autoimmune Uveitis
|
journal
|
June 2013 |
Features and development of Coot
|
journal
|
March 2010 |
Interleukin 23 in the skin: role in psoriasis pathogenesis and selective interleukin 23 blockade as treatment
|
journal
|
March 2018 |
IL-12 regulates the expansion, phenotype, and function of murine NK cells activated by IL-15 and IL-18
|
journal
|
April 2020 |
Interleukin-12 and the regulation of innate resistance and adaptive immunity
|
journal
|
February 2003 |
BacMam system for high-level expression of recombinant soluble and membrane glycoproteins for structural studies
|
journal
|
December 2008 |
Intratumoral Delivery of Interleukin 12 Expression Plasmids with In Vivo Electroporation Is Effective for Colon and Renal Cancer
|
journal
|
July 2001 |
IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways
|
journal
|
June 2007 |
Fiji: an open-source platform for biological-image analysis
|
journal
|
June 2012 |
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
|
journal
|
May 2012 |
WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27
|
journal
|
February 2004 |
IL-23 Is Critical in the Induction but Not in the Effector Phase of Experimental Autoimmune Encephalomyelitis
|
journal
|
February 2007 |
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
|
journal
|
November 2007 |
Hexameric Structure and Assembly of the Interleukin-6/IL-6 -Receptor/gp130 Complex
|
journal
|
June 2003 |
Interleukin 12: still a promising candidate for tumor immunotherapy?
|
journal
|
February 2014 |
IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6
|
journal
|
May 2006 |
Coadministration of interleukin-18 and interleukin-12 induces a fatal inflammatory response in mice: critical role of natural killer cell interferon-γ production and STAT-mediated signal transduction
|
journal
|
August 2000 |
Structural Organization of a Full-Length gp130/LIF-R Cytokine Receptor Transmembrane Complex
|
journal
|
September 2008 |
Cytokine therapy reverses NK cell anergy in MHC-deficient tumors
|
journal
|
October 2014 |
A functional interleukin 12 receptor complex is composed of two -type cytokine receptor subunits
|
journal
|
November 1996 |
Clinical improvement in psoriasis with specific targeting of interleukin-23
|
journal
|
March 2015 |
Role of Interferon-γ in Mediating the Antitumor Efficacy of Interleukin-12
|
journal
|
January 1995 |
IL-12 Deaths: Explanation and a Puzzle
|
journal
|
November 1995 |