Effects of Non-Electrostatic Intermolecular Interactions on the Phase Behavior of pH-Sensitive Polyelectrolyte Complexes

Li, Lu; Srivastava, Samanvaya; Meng, Siqi; Ting, Jeffrey M.; Tirrell, Matthew V.

doi:10.1021/acs.macromol.0c00999

Title: Effects of Non-Electrostatic Intermolecular Interactions on the Phase Behavior of pH-Sensitive Polyelectrolyte Complexes

Journal Article · Fri Aug 28 00:00:00 EDT 2020 · Macromolecules

DOI:https://doi.org/10.1021/acs.macromol.0c00999· OSTI ID:1774601

Li, Lu ^[1];

^[2];

^[1];

^[1]; Tirrell, Matthew V. ^[3]

Univ. of Chicago, IL (United States)
Univ. of California, Los Angeles, CA (United States)
Univ. of Chicago, IL (United States); Argonne National Lab. (ANL), Lemont, IL (United States)

Polyelectrolyte complexes (PECs) offer enormous material tunability and desirable functionalities, and consequently have found broad utility in biomedical and material industries. While poly(acrylic acid) (PAA) and poly( allylamine hydrochloride) (PAH) are a commonly used pairing, various aspects of the phase behavior of PAA-PAH complexes have not been sufficiently quantified. In this work, we present a comprehensive experimental study depicting the binodal phase boundaries for the PAA-PAH complexes prepared under acidic, neutral, and basic conditions using thermogravimetric analysis, turbidimetry, and optical microscopy. Under neutral and basic conditions, phase behaviors of the complexes were largely similar to one another and followed general expectations of PEC phase behavior, except for unusually high resistance to disruption of the complex with added salt. Stable complexes are observed up to 4 M NaCl concentrations. Under acidic conditions, strikingly different phase behaviors of the PAA-PAH complexes were observed. The polymer content in the complex phase increased initially, followed by an expected decrease as salt was added to the complexes. This behavior may result from a combination of associative phase separation of PAA and PAH chains, influenced by electrostatic interactions, and segregative phase separation, which can be ascribed to the influence of a combination of the hydrophobic interactions of the aliphatic polymer backbone and the interpolymer hydrogen bonding of unionized acrylic monomer units. Our systematic investigations over a range of pH detailing these discrepancies in the PAA-PAH phase behavior are expected to clarify the inconsistencies among the reports in the literature and provide the material design strategies for practical use of the PAA-PAH complexes and multilayer assemblies.

View Accepted Manuscript (DOE)

Cite

Export

Save

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States)

Sponsoring Organization:: National Science Foundation (NSF); National Institute of Standards and Technology (NIST); USDOE

Grant/Contract Number:: AC02-06CH11357; 70NANB19H005; DMR-1420709

OSTI ID:: 1774601

Journal Information:: Macromolecules, Vol. 53, Issue 18; ISSN 0024-9297

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

References (78)

Tunable adsorption of bovine serum albumin by annealed cationic spherical polyelectrolyte brushes Wang, Siyi; Chen, Kaimin; Kayitmazer, A. Basak Colloids and Surfaces B: Biointerfaces, Vol. 107 https://doi.org/10.1016/j.colsurfb.2013.02.026	journal	July 2013
Diffusion of Sites versus Polymers in Polyelectrolyte Complexes and Multilayers Fares, Hadi M.; Schlenoff, Joseph B. Journal of the American Chemical Society, Vol. 139, Issue 41 https://doi.org/10.1021/jacs.7b07905	journal	October 2017
Single- and Multicompartment Hollow Polyelectrolyte Complex Microcapsules by One-Step Spraying Wang, Qifeng; Schlenoff, Joseph B. Advanced Materials, Vol. 27, Issue 12 https://doi.org/10.1002/adma.201405376	journal	February 2015
Complex coacervation in sulfated polyvinyl alcohol- aminoacetalyzed polyvinyl alcohol system: II. Formation of coacervate droplets Sato, Hiroko; Nakajima, Akio Colloid and Polymer Science, Vol. 252, Issue 11 https://doi.org/10.1007/bf01566615	journal	November 1974
Structural Evolution of Polyelectrolyte Complex Core Micelles and Ordered-Phase Bulk Materials Krogstad, Daniel V.; Lynd, Nathaniel A.; Miyajima, Daigo Macromolecules, Vol. 47, Issue 22 https://doi.org/10.1021/ma5017852	journal	November 2014
Intrinsic Viscosities of Polyelectrolytes. Poly-(acrylic Acid) Flory, Paul J.; Osterheld, Jean E. The Journal of Physical Chemistry, Vol. 58, Issue 8 https://doi.org/10.1021/j150518a014	journal	August 1954
Growth Kinetics of Polyelectrolyte Complexes Formed from Oppositely-Charged Homopolymers Studied by Time-Resolved Ultra-Small-Angle X-ray Scattering Takahashi, Rintaro; Narayanan, Theyencheri; Sato, Takahiro The Journal of Physical Chemistry Letters, Vol. 8, Issue 4 https://doi.org/10.1021/acs.jpclett.6b02957	journal	January 2017
Binodal Compositions of Polyelectrolyte Complexes Spruijt, Evan; Westphal, Adrie H.; Borst, Jan Willem Macromolecules, Vol. 43, Issue 15 https://doi.org/10.1021/ma101031t	journal	August 2010
Gel phase formation in dilute triblock copolyelectrolyte complexes Srivastava, Samanvaya; Andreev, Marat; Levi, Adam E. Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/ncomms14131	journal	February 2017
Modeling competitive substitution in a polyelectrolyte complex Peng, B.; Muthukumar, M. The Journal of Chemical Physics, Vol. 143, Issue 24 https://doi.org/10.1063/1.4936256	journal	December 2015
Polyelectrolyte complexes: Bulk phases and colloidal systems Gucht, Jasper van der; Spruijt, Evan; Lemmers, Marc Journal of Colloid and Interface Science, Vol. 361, Issue 2 https://doi.org/10.1016/j.jcis.2011.05.080	journal	September 2011
Mechanomutable properties of a PAA/PAH polyelectrolyte complex: rate dependence and ionization effects on tunable adhesion strength Cranford, Steven W.; Ortiz, Christine; Buehler, Markus J. Soft Matter, Vol. 6, Issue 17 https://doi.org/10.1039/c0sm00095g	journal	January 2010
Role of electrostatic correlations in polyelectrolyte charge association Friedowitz, Sean; Salehi, Ali; Larson, Ronald G. The Journal of Chemical Physics, Vol. 149, Issue 16 https://doi.org/10.1063/1.5034454	journal	October 2018
Sequestration of Methylene Blue into Polyelectrolyte Complex Coacervates Zhao, Mengmeng; Zacharia, Nicole S. Macromolecular Rapid Communications, Vol. 37, Issue 15 https://doi.org/10.1002/marc.201600244	journal	June 2016
The phase-separation behaviour of aqueous solutions of polyacrylic acid and its partial sodium salts in the presence of sodium chloride Buscall, R.; Corner, T. European Polymer Journal, Vol. 18, Issue 11 https://doi.org/10.1016/0014-3057(82)90084-2	journal	January 1982
PRISM-Based Theory of Complex Coacervation: Excluded Volume versus Chain Correlation Perry, Sarah L.; Sing, Charles E. Macromolecules, Vol. 48, Issue 14 https://doi.org/10.1021/acs.macromol.5b01027	journal	July 2015
Tunable Coacervation of Well-Defined Homologous Polyanions and Polycations by Local Polarity Lou, Junzhe; Friedowitz, Sean; Qin, Jian ACS Central Science, Vol. 5, Issue 3 https://doi.org/10.1021/acscentsci.8b00964	journal	February 2019
Electrospinning Cargo-Containing Polyelectrolyte Complex Fibers: Correlating Molecular Interactions to Complex Coacervate Phase Behavior and Fiber Formation Meng, Xiangxi; Schiffman, Jessica D.; Perry, Sarah L. Macromolecules, Vol. 51, Issue 21 https://doi.org/10.1021/acs.macromol.8b01709	journal	October 2018
On the Benefits of Rubbing Salt in the Cut: Self-Healing of Saloplastic PAA/PAH Compact Polyelectrolyte Complexes Reisch, Andreas; Roger, Emilie; Phoeung, Thida Advanced Materials, Vol. 26, Issue 16 https://doi.org/10.1002/adma.201304991	journal	January 2014
Structure, Morphology, and Rheology of Polyelectrolyte Complex Hydrogels Formed by Self-Assembly of Oppositely Charged Triblock Polyelectrolytes Srivastava, Samanvaya; Levi, Adam E.; Goldfeld, David J. Macromolecules, Vol. 53, Issue 14 https://doi.org/10.1021/acs.macromol.0c00847	journal	July 2020
A statistical theory of weakly charged polyelectrolytes: fluctuations, equation of state and microphase separation Borue, V. Yu.; Erukhimovich, I. Ya. Macromolecules, Vol. 21, Issue 11 https://doi.org/10.1021/ma00189a019	journal	November 1988
Non-equilibrium phenomena and kinetic pathways in self-assembled polyelectrolyte complexes Wu, Hao; Ting, Jeffrey M.; Werba, Olivia The Journal of Chemical Physics, Vol. 149, Issue 16 https://doi.org/10.1063/1.5039621	journal	October 2018
The Effect of Salt on the Complex Coacervation of Vinyl Polyelectrolytes Perry, Sarah; Li, Yue; Priftis, Dimitrios Polymers, Vol. 6, Issue 6 https://doi.org/10.3390/polym6061756	journal	June 2014
Entropy and enthalpy of polyelectrolyte complexation: Langevin dynamics simulations Ou, Zhaoyang; Muthukumar, M. The Journal of Chemical Physics, Vol. 124, Issue 15 https://doi.org/10.1063/1.2178803	journal	April 2006
Thermodynamic Characterization of Acacia Gum−β-Lactoglobulin Complex Coacervation Aberkane, Leïla; Jasniewski, Jordane; Gaiani, Claire Langmuir, Vol. 26, Issue 15 https://doi.org/10.1021/la100705d	journal	August 2010
Precipitation of oppositely charged polyelectrolytes in salt solutions Kudlay, Alexander; Olvera de la Cruz, Monica The Journal of Chemical Physics, Vol. 120, Issue 1 https://doi.org/10.1063/1.1629271	journal	January 2004
Molecular Connectivity and Correlation Effects on Polymer Coacervation Radhakrishna, Mithun; Basu, Kush; Liu, Yalin Macromolecules, Vol. 50, Issue 7 https://doi.org/10.1021/acs.macromol.6b02582	journal	March 2017
Engineering Peptide-Based Polyelectrolyte Complexes with Increased Hydrophobicity Tabandeh, Sara; Leon, Lorraine Molecules, Vol. 24, Issue 5 https://doi.org/10.3390/molecules24050868	journal	March 2019
Complex Coacervate of Weakly Charged Polyelectrolytes: Diagram of States Rumyantsev, Artem M.; Zhulina, Ekaterina B.; Borisov, Oleg V. Macromolecules, Vol. 51, Issue 10 https://doi.org/10.1021/acs.macromol.8b00342	journal	May 2018
The Polyelectrolyte Complex/Coacervate Continuum Wang, Qifeng; Schlenoff, Joseph B. Macromolecules, Vol. 47, Issue 9 https://doi.org/10.1021/ma500500q	journal	April 2014
pH and Salt Effects on the Associative Phase Separation of Oppositely Charged Polyelectrolytes Jha, Prateek; Desai, Priyanka; Li, Jingyi Polymers, Vol. 6, Issue 5 https://doi.org/10.3390/polym6051414	journal	May 2014
The influence of ionic strength and mixing ratio on the colloidal stability of PDAC/PSS polyelectrolyte complexes Zhang, Yanpu; Yildirim, Erol; Antila, Hanne S. Soft Matter, Vol. 11, Issue 37 https://doi.org/10.1039/c5sm01184a	journal	January 2015
Phosphorylation-mediated RNA/peptide complex coacervation as a model for intracellular liquid organelles Aumiller, William M.; Keating, Christine D. Nature Chemistry, Vol. 8, Issue 2 https://doi.org/10.1038/nchem.2414	journal	December 2015
Evidence of a two-step process and pathway dependency in the thermodynamics of poly(diallyldimethylammonium chloride)/poly(sodium acrylate) complexation Vitorazi, L.; Ould-Moussa, N.; Sekar, S. Soft Matter, Vol. 10, Issue 47 https://doi.org/10.1039/c4sm01461h	journal	January 2014
Phase separation in polyelectrolyte solutions. Theory of complex coacervation Overbeek, J. T. G.; Voorn, M. J. Journal of Cellular and Comparative Physiology, Vol. 49, Issue S1 https://doi.org/10.1002/jcp.1030490404	journal	May 1957
Polyelectrolyte complex layers: a promising concept for anti-fouling coatings verified byin-situ ATR-FTIR spectroscopy Müller, Martin; Rieser, Theresia; Lunkwitz, Klaus Macromolecular Rapid Communications, Vol. 20, Issue 12 https://doi.org/10.1002/(sici)1521-3927(19991201)20:12<607::aid-marc607>3.0.co;2-z	journal	December 1999
Role of Associative Charging in the Entropy–Energy Balance of Polyelectrolyte Complexes Rathee, Vikramjit S.; Sidky, Hythem; Sikora, Benjamin J. Journal of the American Chemical Society, Vol. 140, Issue 45 https://doi.org/10.1021/jacs.8b08649	journal	October 2018
Ideal Mixing in Polyelectrolyte Complexes and Multilayers: Entropy Driven Assembly Bucur, Claudiu B.; Sui, Zhijie; Schlenoff, Joseph B. Journal of the American Chemical Society, Vol. 128, Issue 42 https://doi.org/10.1021/ja064532c	journal	October 2006
Effect of small molecules on the phase behavior and coacervation of aqueous solutions of poly(diallyldimethylammonium chloride) and poly(sodium 4-styrene sulfonate) Huang, Shuyue; Zhao, Mengmeng; Dawadi, Mahesh B. Journal of Colloid and Interface Science, Vol. 518 https://doi.org/10.1016/j.jcis.2018.02.029	journal	May 2018
Molecular weight fractionation and the self-suppression of complex coacervation Veis, Arthur; Bodor, Edward; Mussell, Shirley Biopolymers, Vol. 5, Issue 1 https://doi.org/10.1002/bip.1967.360050106	journal	January 1967
50th Anniversary Perspective : A Perspective on Polyelectrolyte Solutions Muthukumar, M. Macromolecules, Vol. 50, Issue 24 https://doi.org/10.1021/acs.macromol.7b01929	journal	December 2017
Phase Behavior and Salt Partitioning in Polyelectrolyte Complex Coacervates Li, Lu; Srivastava, Samanvaya; Andreev, Marat Macromolecules, Vol. 51, Issue 8 https://doi.org/10.1021/acs.macromol.8b00238	journal	April 2018
Complexation of Oppositely Charged Polyelectrolytes: Effect of Ion Pair Formation Kudlay, Alexander; Ermoshkin, Alexander V.; Olvera de la Cruz, Monica Macromolecules, Vol. 37, Issue 24 https://doi.org/10.1021/ma048519t	journal	November 2004
Polymer compatibility and interpolymer association in the poly(acrylic acid)–polyacrylamide–water ternary system Eustace, D. J.; Siano, D. B.; Drake, E. N. Journal of Applied Polymer Science, Vol. 35, Issue 3 https://doi.org/10.1002/app.1988.070350311	journal	February 1988
Criticality and Connectivity in Macromolecular Charge Complexation Qin, Jian; de Pablo, Juan J. Macromolecules, Vol. 49, Issue 22 https://doi.org/10.1021/acs.macromol.6b02113	journal	November 2016
A Molecular Thermodynamic Model of Complexation in Mixtures of Oppositely Charged Polyelectrolytes with Explicit Account of Charge Association/Dissociation Salehi, Ali; Larson, Ronald G. Macromolecules, Vol. 49, Issue 24 https://doi.org/10.1021/acs.macromol.6b01464	journal	December 2016
Relationship between Polyelectrolyte Bulk Complexation and Kinetics of Their Layer-by-Layer Assembly Salehi, Ali; Desai, Priyanka S.; Li, Jingyi Macromolecules, Vol. 48, Issue 2 https://doi.org/10.1021/ma502273a	journal	January 2015
Segmental Dynamics of Poly(acrylic acid) in Polyelectrolyte Complex Coacervates Studied by Spin-Label EPR Spectroscopy Lappan, Uwe; Wiesner, Brigitte; Scheler, Ulrich Macromolecules, Vol. 49, Issue 22 https://doi.org/10.1021/acs.macromol.6b01863	journal	November 2016
Phase Behavior and Coacervation of Aqueous Poly(acrylic acid)−Poly(allylamine) Solutions Chollakup, Rungsima; Smitthipong, Wirasak; Eisenbach, Claus D. Macromolecules, Vol. 43, Issue 5 https://doi.org/10.1021/ma902144k	journal	March 2010
Unusually Stable Hysteresis in the pH-Response of Poly(Acrylic Acid) Brushes Confined within Nanoporous Block Polymer Thin Films Weidman, Jacob L.; Mulvenna, Ryan A.; Boudouris, Bryan W. Journal of the American Chemical Society, Vol. 138, Issue 22 https://doi.org/10.1021/jacs.6b01618	journal	May 2016
Synthesis and Assembly of Designer Styrenic Diblock Polyelectrolytes Ting, Jeffrey M.; Wu, Hao; Herzog-Arbeitman, Abraham ACS Macro Letters, Vol. 7, Issue 6 https://doi.org/10.1021/acsmacrolett.8b00346	journal	May 2018
Interfacial Energy of Polypeptide Complex Coacervates Measured via Capillary Adhesion Priftis, Dimitrios; Farina, Robert; Tirrell, Matthew Langmuir, Vol. 28, Issue 23 https://doi.org/10.1021/la300769d	journal	May 2012
Protein Encapsulation via Polypeptide Complex Coacervation Black, Katie A.; Priftis, Dimitrios; Perry, Sarah L. ACS Macro Letters, Vol. 3, Issue 10 https://doi.org/10.1021/mz500529v	journal	October 2014
Polymer physics of intracellular phase transitions Brangwynne, Clifford P.; Tompa, Peter; Pappu, Rohit V. Nature Physics, Vol. 11, Issue 11 https://doi.org/10.1038/nphys3532	journal	November 2015
Thermodynamic Characterization of Polypeptide Complex Coacervation Priftis, Dimitrios; Laugel, Nicolas; Tirrell, Matthew Langmuir, Vol. 28, Issue 45 https://doi.org/10.1021/la302729r	journal	October 2012
Polyelectrolyte Molecular Weight and Salt Effects on the Phase Behavior and Coacervation of Aqueous Solutions of Poly(acrylic acid) Sodium Salt and Poly(allylamine) Hydrochloride Chollakup, Rungsima; Beck, John B.; Dirnberger, Klaus Macromolecules, Vol. 46, Issue 6 https://doi.org/10.1021/ma202172q	journal	March 2013
Tunable, High Modulus Hydrogels Driven by Ionic Coacervation Hunt, Jasmine N.; Feldman, Kathleen E.; Lynd, Nathaniel A. Advanced Materials, Vol. 23, Issue 20 https://doi.org/10.1002/adma.201004230	journal	April 2011
Base−Acid Equilibria in Polyelectrolyte Systems: From Weak Polyelectrolytes to Interpolyelectrolyte Complexes and Multilayered Polyelectrolyte Shells Petrov, Alexander I.; Antipov, Alexei A.; Sukhorukov, Gleb B. Macromolecules, Vol. 36, Issue 26 https://doi.org/10.1021/ma034516p	journal	December 2003
Salting-Out and Salting-In of Polyelectrolyte Solutions: A Liquid-State Theory Study Zhang, Pengfei; Alsaifi, Nayef M.; Wu, Jianzhong Macromolecules, Vol. 49, Issue 24 https://doi.org/10.1021/acs.macromol.6b02160	journal	December 2016
Electrospinning Nanofibers from Chitosan/Hyaluronic Acid Complex Coacervates Sun, Juanfeng; Perry, Sarah L.; Schiffman, Jessica D. Biomacromolecules, Vol. 20, Issue 11 https://doi.org/10.1021/acs.biomac.9b01072	journal	September 2019
Driving Forces for Oppositely Charged Polyion Association in Aqueous Solutions: Enthalpic, Entropic, but Not Electrostatic Fu, Jingcheng; Schlenoff, Joseph B. Journal of the American Chemical Society, Vol. 138, Issue 3 https://doi.org/10.1021/jacs.5b11878	journal	January 2016
Composition and property tunable ternary coacervate: branched polyethylenimine and a binary mixture of a strong and weak polyelectrolyte Zhao, Mengmeng; Xia, Xuhui; Mao, Jingyi Molecular Systems Design & Engineering, Vol. 4, Issue 1 https://doi.org/10.1039/c8me00069g	journal	January 2019
Complex coacervation in sulfated polyvinyl alcohol-amino acetalyzed polyvinyl alcohol system: I. Conditions for complex coacervation Sato, H.; Nakajima, A. Colloid and Polymer Science, Vol. 252, Issue 4 https://doi.org/10.1007/bf01551150	journal	April 1974
Effect of Water on the Thermal Transition Observed in Poly(allylamine hydrochloride)–Poly(acrylic acid) Complexes Zhang, Yanpu; Li, Fei; Valenzuela, Luis D. Macromolecules, Vol. 49, Issue 19 https://doi.org/10.1021/acs.macromol.6b00742	journal	September 2016
Influence of Hydrophobicity on Polyelectrolyte Complexation Sadman, Kazi; Wang, Qifeng; Chen, Yaoyao Macromolecules, Vol. 50, Issue 23 https://doi.org/10.1021/acs.macromol.7b02031	journal	November 2017
Ion-Pairing Strength in Polyelectrolyte Complexes Fu, Jingcheng; Fares, Hadi M.; Schlenoff, Joseph B. Macromolecules, Vol. 50, Issue 3 https://doi.org/10.1021/acs.macromol.6b02445	journal	January 2017
Lower Critical Solution Temperature in Polyelectrolyte Complex Coacervates Ali, Samim; Bleuel, Markus; Prabhu, Vivek M. ACS Macro Letters, Vol. 8, Issue 3 https://doi.org/10.1021/acsmacrolett.8b00952	journal	February 2019
Tuning chain interaction entropy in complex coacervation using polymer stiffness, architecture, and salt valency Lytle, Tyler K.; Sing, Charles E. Molecular Systems Design & Engineering, Vol. 3, Issue 1 https://doi.org/10.1039/c7me00108h	journal	January 2018
RNA-Based Coacervates as a Model for Membraneless Organelles: Formation, Properties, and Interfacial Liposome Assembly Aumiller, William M.; Pir Cakmak, Fatma; Davis, Bradley W. Langmuir, Vol. 32, Issue 39 https://doi.org/10.1021/acs.langmuir.6b02499	journal	September 2016
Phase separation drives heterochromatin domain formation Strom, Amy R.; Emelyanov, Alexander V.; Mir, Mustafa Nature, Vol. 547, Issue 7662 https://doi.org/10.1038/nature22989	journal	June 2017
Weak polyelectrolyte complexation driven by associative charging Rathee, Vikramjit S.; Zervoudakis, Aristotle J.; Sidky, Hythem The Journal of Chemical Physics, Vol. 148, Issue 11 https://doi.org/10.1063/1.5017941	journal	March 2018
Complex Coacervation: Chemically Stable Fibers Electrospun from Aqueous Polyelectrolyte Solutions Meng, Xiangxi; Perry, Sarah L.; Schiffman, Jessica D. ACS Macro Letters, Vol. 6, Issue 5 https://doi.org/10.1021/acsmacrolett.7b00173	journal	April 2017
Charge-Density-Dominated Phase Behavior and Viscoelasticity of Polyelectrolyte Complex Coacervates Huang, Jun; Morin, Frances J.; Laaser, Jennifer E. Macromolecules, Vol. 52, Issue 13 https://doi.org/10.1021/acs.macromol.9b00036	journal	June 2019
Sequence and entropy-based control of complex coacervates Chang, Li-Wei; Lytle, Tyler K.; Radhakrishna, Mithun Nature Communications, Vol. 8, Issue 1 https://doi.org/10.1038/s41467-017-01249-1	journal	November 2017
Polyelectrolyte chain dimensions and concentration fluctuations near phase boundaries Prabhu, V. M.; Muthukumar, M.; Wignall, G. D. The Journal of Chemical Physics, Vol. 119, Issue 7 https://doi.org/10.1063/1.1592496	journal	August 2003
Salt Partitioning in Complex Coacervation of Symmetric Polyelectrolytes Zhang, Pengfei; Shen, Kevin; Alsaifi, Nayef M. Macromolecules, Vol. 51, Issue 15 https://doi.org/10.1021/acs.macromol.8b00726	journal	July 2018
Electrically-responsive deformation of polyelectrolyte complex (PEC) fibrous membrane Boas, Mor; Burman, Michael; Yarin, Alexander L. Polymer, Vol. 158 https://doi.org/10.1016/j.polymer.2018.10.064	journal	December 2018
Lower Critical Solution Temperature Behavior in Polyelectrolyte Complex Coacervates Adhikari, Sabin; Prabhu, Vivek M.; Muthukumar, Murugappan Macromolecules, Vol. 52, Issue 18 https://doi.org/10.1021/acs.macromol.9b01201	journal	August 2019

Similar Records

The Effect of Salt on the Complex Coacervation of Vinyl Polyelectrolytes

Journal Article · Sun Jun 01 00:00:00 EDT 2014 · Polymers · OSTI ID:1774601

Perry, Sarah; Li, Yue; Priftis, Dimitrios; +2 more

Electrochemical and in situ ellipsometric investigation of the permeability and stability of layered polyelectrolyte films

Journal Article · Tue Feb 22 00:00:00 EST 2000 · Langmuir · OSTI ID:1774601

Harris, J J; Bruening, M L

Collective epithelial cell sheet adhesion and migration on polyelectrolyte multilayers with uniform and gradients of compliance

Journal Article · Mon Aug 01 00:00:00 EDT 2016 · Experimental Cell Research · OSTI ID:1774601

Martinez, Jessica S.; Schlenoff, Joseph B.

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Salts
Molecular mechanics
Noncovalent interactions
Polyelectrolytes
Polymers

Title: Effects of Non-Electrostatic Intermolecular Interactions on the Phase Behavior of pH-Sensitive Polyelectrolyte Complexes

Citation Formats

References (78)

Similar Records

Related Subjects