Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1
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January 2019 |
Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
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November 2016 |
The structural basis for partitioning of the XRCC1/DNA ligase III-α BRCT-mediated dimer complexes
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June 2011 |
DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
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June 2011 |
RsrA, an anti-sigma factor regulated by redox change
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August 1999 |
Spatial and Temporal Cellular Responses to Single-Strand Breaks in Human Cells
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June 2003 |
DNA Ligase III Is Recruited to DNA Strand Breaks by a Zinc Finger Motif Homologous to That of Poly(ADP-ribose) Polymerase: IDENTIFICATION OF TWO FUNCTIONALLY DISTINCT DNA BINDING REGIONS WITHIN DNA LIGASE III
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July 1999 |
Role of a BRCT domain in the interaction of DNA ligase III-α with the DNA repair protein XRCC1
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July 1998 |
NEIL2-initiated, APE-independent repair of oxidized bases in DNA: Evidence for a repair complex in human cells
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December 2006 |
Structural basis for AcrVA4 inhibition of specific CRISPR-Cas12a
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August 2019 |
Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase
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August 2009 |
Domain specific interaction in the XRCC1-DNA polymerase beta complex
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May 2000 |
Two DNA-binding and Nick Recognition Modules in Human DNA Ligase III
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April 2008 |
Physical and Functional Interaction between DNA Ligase IIIα and Poly(ADP-Ribose) Polymerase 1 in DNA Single-Strand Break Repair
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August 2003 |
Solution Structure and DNA Binding of the Zinc-finger Domain from DNA Ligase IIIα
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August 2004 |
A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses
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March 2007 |
CHIP-Mediated Degradation and DNA Damage-Dependent Stabilization Regulate Base Excision Repair Proteins
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February 2008 |
Prevention of overfitting in cryo-EM structure determination
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July 2012 |
APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks
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March 2007 |
Local analysis of strains and rotations for macromolecular electron microscopy maps
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July 2016 |
Single-strand break repair and genetic disease
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August 2008 |
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
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March 2011 |
Role of XRCC1 in the Coordination and Stimulation of Oxidative DNA Damage Repair Initiated by the DNA Glycosylase hOGG1
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November 2003 |
DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination
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January 2000 |
Accurate SAXS Profile Computation and its Assessment by Contrast Variation Experiments
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August 2013 |
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
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journal
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August 2007 |
FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles
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May 2016 |
Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining
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June 2015 |
Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and Rapamycin
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journal
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January 1993 |
Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks
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April 2008 |
UCSF Chimera?A visualization system for exploratory research and analysis
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January 2004 |
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS)
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July 2009 |
AP Endonuclease-Independent DNA Base Excision Repair in Human Cells
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July 2004 |
The Electron Microscopy eXchange (EMX) initiative
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May 2016 |
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates
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September 2006 |
Mutation of a BRCT domain selectively disrupts DNA single-strand break repair in noncycling Chinese hamster ovary cells
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November 2000 |
Two Pathways for Base Excision Repair in Mammalian Cells
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April 1996 |
Comparative Protein Modelling by Satisfaction of Spatial Restraints
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December 1993 |
An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination.
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February 1997 |
Mitochondrial DNA ligase III function is independent of Xrcc1
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October 2000 |
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source
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January 2013 |
Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.
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December 1990 |
An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III.
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January 1994 |
XRCC1 Polypeptide Interacts with DNA Polymerase and Possibly Poly (ADP-Ribose) Polymerase, and DNA Ligase III Is a Novel Molecular 'Nick-Sensor' In Vitro
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November 1996 |
Mutations in PNKP cause microcephaly, seizures and defects in DNA repair
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January 2010 |
SUMOylation coordinates BERosome assembly in active DNA demethylation during cell differentiation
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December 2018 |
In situ analysis of repair processes for oxidative DNA damage in mammalian cells
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September 2004 |
Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
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journal
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October 2019 |
High-Throughput SAXS for the Characterization of Biomolecules in Solution: A Practical Approach
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book
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October 2013 |
Sealing of Chromosomal DNA Nicks during Nucleotide Excision Repair Requires XRCC1 and DNA Ligase IIIα in a Cell-Cycle-Specific Manner
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journal
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July 2007 |
Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein.
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December 1996 |
FoXS: a web server for rapid computation and fitting of SAXS profiles
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May 2010 |
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
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August 2020 |
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
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December 2012 |
DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair
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March 2011 |
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
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December 2016 |
The Human DNA Ligase III Gene Encodes Nuclear and Mitochondrial Proteins
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May 1999 |
Direct interaction between XRCC1 and UNG2 facilitates rapid repair of uracil in DNA by XRCC1 complexes
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July 2010 |
Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells
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January 1995 |
The FHA domain of aprataxin interacts with the C-terminal region of XRCC1
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December 2004 |
Structure of an XRCC1 BRCT domain: a new protein-protein interaction module
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November 1998 |
Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law
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April 2011 |
XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair
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July 2010 |
Structure and flexibility within proteins as identified through small angle X-ray scattering
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January 2009 |
Automated electron microscope tomography using robust prediction of specimen movements
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October 2005 |
Biophysical Characterization of Human XRCC1 and Its Binding to Damaged and Undamaged DNA †
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December 2004 |
Accurate assessment of mass, models and resolution by small-angle scattering
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April 2013 |
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
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February 2017 |
Human Mre11/Human Rad50/Nbs1 and DNA Ligase IIIα/XRCC1 Protein Complexes Act Together in an Alternative Nonhomologous End Joining Pathway
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August 2011 |
XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions
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November 2001 |
Disconnecting XRCC1 and DNA ligase III
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July 2011 |
A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA
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October 2006 |
A New XRCC1-Containing Complex and Its Role in Cellular Survival of Methyl Methanesulfonate Treatment
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October 2004 |
Human DNA Ligase III Recognizes DNA Ends by Dynamic Switching between Two DNA-Bound States
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July 2010 |
XRCC1 interactions with multiple DNA glycosylases: A model for its recruitment to base excision repair
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July 2005 |
XRCC1 protein; Form and function
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journal
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September 2019 |
Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering
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February 2010 |