The “Virtual Digital Twins” Concept in Precision Nutrition
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journal
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August 2020 |
Towards personalized, tumour-specific, therapeutic vaccines for cancer
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journal
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December 2017 |
A reaction–diffusion model for oncolytic M1 virotherapy with distributed delays
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journal
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January 2020 |
Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas
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journal
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July 2019 |
Therapeutic Cancer Vaccines
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book
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January 2013 |
A Computational Model of Neoadjuvant PD-1 Inhibition in Non-Small Cell Lung Cancer
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journal
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June 2019 |
FDA Advisory Meeting Clinical Pharmacology Review Utilizes a Quantitative Systems Pharmacology (QSP) Model: A Watershed Moment?
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journal
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March 2015 |
Asymmetric paralog evolution between the “cryptic” gene Bmp16 and its well-studied sister genes Bmp2 and Bmp4
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journal
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February 2019 |
Modelling heterogeneity in viral-tumour dynamics: The effects of gene-attenuation on viral characteristics
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October 2018 |
Clinical trial of attenuated vaccinia virus AS strain in the treatment of advanced adenocarcinoma: Report on two cases
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February 1987 |
Alternate virtual populations elucidate the type I interferon signature predictive of the response to rituximab in rheumatoid arthritis
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January 2013 |
SLIM: Simultaneous Logic-in-Memory Computing Exploiting Bilayer Analog OxRAM Devices
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February 2020 |
Mathematical and Computational Modeling for Tumor Virotherapy with Mediated Immunity
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June 2017 |
Oncolytic vaccinia virus for the treatment of cancer
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February 2011 |
Pexa-Vec double agent engineered vaccinia: oncolytic and active immunotherapeutic
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August 2015 |
A mathematical model for tumor growth and treatment using virotherapy
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journal
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January 2020 |
In Silico Clinical Trials: A Possible Response to Complexity in Pharmacology
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book
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February 2020 |
Randomized, Open-Label Phase II Study Evaluating the Efficacy and Safety of Talimogene Laherparepvec in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced, Unresectable Melanoma
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journal
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June 2018 |
Determinants of combination GM-CSF immunotherapy and oncolytic virotherapy success identified through in silico treatment personalization
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November 2019 |
Chemokine Expression From Oncolytic Vaccinia Virus Enhances Vaccine Therapies of Cancer
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journal
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April 2011 |
Development and applications of oncolytic Maraba virus vaccines
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journal
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January 2018 |
A Novel Therapeutic Regimen to Eradicate Established Solid Tumors with an Effective Induction of Tumor-Specific Immunity
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journal
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October 2012 |
Translational approaches to treating dynamical diseases through in silico clinical trials
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journal
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December 2020 |
Talimogene laherparepvec: review of its mechanism of action and clinical efficacy and safety
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journal
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June 2019 |
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
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journal
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February 2013 |
Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced Melanoma
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journal
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September 2015 |
Mathematical modelling of a hypoxia-regulated oncolytic virus delivered by tumour-associated macrophages
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January 2019 |
Cell population heterogeneity and evolution towards drug resistance in cancer: Biological and mathematical assessment, theoretical treatment optimisation
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November 2016 |
A delay differential equation model for tumor growth
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journal
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August 2003 |
Oncolytic Viruses: Priming Time for Cancer Immunotherapy
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journal
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July 2019 |
Estimating long-term effects of treatment from placebo-controlled trials with an extension period, using virtual twins
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journal
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March 2010 |
Synergistic Interaction Between Oncolytic Viruses Augments Tumor Killing
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journal
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May 2010 |
Modeling the Spatiotemporal Dynamics of Oncolytic Viruses and Radiotherapy as a Treatment for Cancer
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journal
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April 2020 |
From the evolution of toxin resistance to virtual clinical trials: the role of mathematical models in oncology
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journal
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June 2010 |
First-in-man Study of Western Reserve Strain Oncolytic Vaccinia Virus: Safety, Systemic Spread, and Antitumor Activity
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journal
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January 2015 |
Role of Mechanotransduction and Tension in T Cell Function
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journal
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November 2018 |
Therapeutic Cancer Vaccine and Combinations With Antiangiogenic Therapies and Immune Checkpoint Blockade
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journal
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March 2019 |
Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus
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journal
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October 2009 |
Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy
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journal
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January 2018 |
Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy
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journal
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October 2016 |
Lung aerosol dynamics of airborne influenza A virus-laden droplets and the resultant immune system responses: An in silico study
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journal
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August 2019 |
A mathematical model that combines chemotherapy and oncolytic virotherapy as an alternative treatment against a glioma
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journal
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November 2019 |
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
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journal
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July 2000 |
Virus-Induced Transient Immune Suppression and the Inhibition of T Cell Proliferation by Type I Interferon
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journal
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April 2011 |
Efficient Generation and Selection of Virtual Populations in Quantitative Systems Pharmacology Models
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journal
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March 2016 |
Application of control theory in a delayed-infection and immune-evading oncolytic virotherapy
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journal
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January 2020 |
Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer
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journal
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July 2019 |
Potentiating Cancer Immunotherapy Using an Oncolytic Virus
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journal
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August 2010 |
Evaluating optimal therapy robustness by virtual expansion of a sample population, with a case study in cancer immunotherapy
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journal
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July 2017 |
Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer
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journal
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December 2012 |
In silico simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model
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journal
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May 2019 |
Brief Communication; A Heterologous Oncolytic Bacteria-Virus Prime-Boost Approach for Anticancer Vaccination in Mice
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journal
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January 2018 |
Oncolytic vesicular stomatitis virus quantitatively and qualitatively improves primary CD8 + T-cell responses to anticancer vaccines
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journal
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August 2013 |