An overview of the gene regulatory network controlling trichome development in the model plant, Arabidopsis

Pattanaik, Sitakanta; Patra, Barunava; Singh, Sanjay Kumar; Yuan, Ling

doi:10.3389/fpls.2014.00259

Title: An overview of the gene regulatory network controlling trichome development in the model plant, Arabidopsis

Journal Article · Thu Jun 05 00:00:00 EDT 2014 · Frontiers in Plant Science

DOI:https://doi.org/10.3389/fpls.2014.00259· OSTI ID:1628256

Pattanaik, Sitakanta ^[1]; Patra, Barunava ^[1]; Singh, Sanjay Kumar ^[1]; Yuan, Ling ^[1]

Univ. of Kentucky, Lexington, KY (United States). Kentucky Tobacco Research and Development Center. Dept. of Plant and Soil Sciences

Trichomes are specialized epidermal cells located on aerial parts of plants and are associated with a wide array of biological processes. Trichomes protect plants from adverse conditions including UV light and herbivore attack and are also an important source of a number of phytochemicals. The simple unicellular trichomes of Arabidopsis serve as an excellent model to study molecular mechanism of cell differentiation and pattern formation in plants. The emerging picture suggests that the developmental process is controlled by a transcriptional network involving three major groups of transcription factors (TFs): the R2R3 MYB, basic helix-loop-helix (bHLH), and WD40 repeat (WDR) protein. These regulatory proteins form a trimeric activator complex that positively regulates trichome development. The single repeat R3 MYBs act as negative regulators of trichome development. They compete with the R2R3 MYBs to bind the bHLH factor and form a repressor complex. In addition to activator–repressor mechanism, a depletion mechanism may operate in parallel during trichome development. In this mechanism, the bHLH factor traps the WDR protein which results in depletion of WDR protein in neighboring cells. Consequently, the cells with high levels of bHLH and WDR proteins are developed into trichomes. A group of C2H2 zinc finger TFs has also been implicated in trichome development. Phytohormones, including gibberellins and jasmonic acid, play significant roles in this developmental process. Recently, microRNAs have been shown to be involved in trichome development. Furthermore, it has been demonstrated that the activities of the key regulatory proteins involved in trichome development are controlled by the 26S/ubiquitin proteasome system (UPS), highlighting the complexity of the regulatory network controlling this developmental process. To complement several excellent recent relevant reviews, this review focuses on the transcriptional network and hormonal interplay controlling trichome development in Arabidopsis.

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Research Organization:: Univ. of California, Oakland, CA (United States)

Sponsoring Organization:: USDOE Advanced Research Projects Agency - Energy (ARPA-E)

Grant/Contract Number:: AR0000204

OSTI ID:: 1628256

Journal Information:: Frontiers in Plant Science, Vol. 5; ISSN 1664-462X

Publisher:: Frontiers Research FoundationCopyright Statement

Country of Publication:: United States

Language:: English

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Title: An overview of the gene regulatory network controlling trichome development in the model plant, Arabidopsis

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