Structural analysis of a therapeutic monoclonal antibody dimer by hydroxyl radical footprinting
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journal
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January 2013 |
TPP1 is a homologue of ciliate TEBP-β and interacts with POT1 to recruit telomerase
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journal
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January 2007 |
Inhibition of telomerase by G-quartet DMA structures
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journal
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April 1991 |
High-Resolution Hydroxyl Radical Protein Footprinting: Biophysics Tool for Drug Discovery
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journal
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May 2018 |
DNA Binding Features of Human POT1: A NONAMER 5′-TAGGGTTAG-3′ MINIMAL BINDING SITE, SEQUENCE SPECIFICITY, AND INTERNAL BINDING TO MULTIMERIC SITES
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journal
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January 2004 |
Monovalent cation-induced structure of telomeric DNA: The G-quartet model
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journal
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December 1989 |
Multiple POT1–TPP1 Proteins Coat and Compact Long Telomeric Single-Stranded DNA
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journal
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July 2011 |
Footprinting protein–DNA complexes using the hydroxyl radical
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journal
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June 2008 |
Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells
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journal
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August 2009 |
Pot1, the Putative Telomere End-Binding Protein in Fission Yeast and Humans
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journal
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May 2001 |
Germline Mutations in Shelterin Complex Genes Are Associated With Familial Glioma
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journal
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December 2014 |
A Protein-Counting Mechanism for Telomere Length Regulation in Yeast
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journal
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February 1997 |
G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding
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journal
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February 2014 |
POT1–TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism
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journal
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July 2016 |
Biophysical and biological properties of quadruplex oligodeoxyribonucleotides
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journal
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April 2003 |
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
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journal
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March 2013 |
Rare missense variants in POT1 predispose to familial cutaneous malignant melanoma
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journal
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March 2014 |
A Survey of Validation Strategies for CRISPR-Cas9 Editing
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journal
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January 2018 |
Measured and calculated CD spectra of G-quartets stacked with the same or opposite polarities
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journal
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March 2008 |
Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
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journal
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November 2004 |
Functional interaction between telomere protein TPP1 and telomerase
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journal
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March 2010 |
Quantitative Mapping of Protein Structure by Hydroxyl Radical Footprinting-Mediated Structural Mass Spectrometry: A Protection Factor Analysis
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journal
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January 2015 |
The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity
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journal
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October 2012 |
Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells
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journal
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August 2009 |
Radiolytic Protein Footprinting with mass Spectrometry to Probe the Structure of Macromolecular Complexes
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journal
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June 2006 |
Finding the end: recruitment of telomerase to telomeres
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journal
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January 2013 |
Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres
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journal
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August 2016 |
The POT1–TPP1 telomere complex is a telomerase processivity factor
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journal
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January 2007 |
TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends
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journal
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August 2012 |
Shelterin: the protein complex that shapes and safeguards human telomeres
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journal
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September 2005 |
Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution
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journal
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January 2006 |
Telomere Extension Occurs at Most Chromosome Ends and Is Uncoupled from Fill-In in Human Cancer Cells
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journal
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August 2009 |
Telomeres and telomerase: their mechanisms of action and the effects of altering their functions
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journal
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November 2004 |
DNA-induced dimerization of the single-stranded DNA binding telomeric protein Pot1 from Schizosaccharomyces pombe
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journal
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September 2011 |
Dynamic peptides of human TPP1 fulfill diverse functions in telomere maintenance
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journal
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September 2016 |
Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro
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journal
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July 2005 |
Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops
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journal
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December 1989 |
G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase
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journal
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March 2011 |
POT1-TPP1 Regulates Telomeric Overhang Structural Dynamics
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journal
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November 2012 |
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
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journal
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September 1988 |
Mammalian Telomeres End in a Large Duplex Loop
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journal
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May 1999 |
A mutation in the POT1 gene is responsible for cardiac angiosarcoma in TP53-negative Li–Fraumeni-like families
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journal
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September 2015 |
Mutations in POT1 predispose to familial cutaneous malignant melanoma: HotSpots
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journal
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May 2014 |
Telomere Length Homeostasis Is Achieved via a Switch between Telomerase- Extendible and -Nonextendible States
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journal
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April 2004 |
Exposing Secrets of Telomere-Telomerase Encounters
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journal
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August 2012 |
Telomeres Do D-Loop–T-Loop
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journal
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May 1999 |
Long G Tails at Both Ends of Human Chromosomes Suggest a C Strand Degradation Mechanism for Telomere Shortening
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journal
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March 1997 |
Human Telomerase Caught in the Act
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journal
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August 2009 |
Cancer chromosomes going to POT1
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journal
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April 2013 |
Telomere Shortening Is Proportional to the Size of the G-rich Telomeric 3′-Overhang
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journal
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April 2000 |
In Vivo Stoichiometry of Shelterin Components
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journal
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October 2009 |
Specificity Requirements for Human Telomere Protein Interaction with Telomerase Holoenzyme
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journal
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August 2012 |
Coordinated Interactions of Multiple POT1-TPP1 Proteins with Telomere DNA
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journal
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April 2013 |
Protein Footprinting Comes of Age: Mass Spectrometry for Biophysical Structure Assessment
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journal
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March 2017 |
TIN2-Tethered TPP1 Recruits Human Telomerase to Telomeres In Vivo
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journal
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April 2010 |