Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
|
journal
|
November 1992 |
Prospective Randomized Trial of Emtricitabine versus Lamivudine Short‐Term Monotherapy in Human Immunodeficiency Virus–Infected Patients
|
journal
|
December 2003 |
Safety and antiviral activity of emtricitabine (FTC) for the treatment of chronic hepatitis B infection: A two-year study
|
journal
|
July 2005 |
Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides.
|
journal
|
April 1993 |
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
|
journal
|
June 1993 |
Evolution of Lamivudine Resistance in Human Immunodeficiency Virus Type 1-Infected Individuals: the Relative Roles of Drift and Selection
|
journal
|
July 2000 |
Nucleotide substitution patterns can predict the requirements for drug-resistance of HIV-1 proteins
|
journal
|
June 1996 |
Molecular Impact of the M184V Mutation in Human Immunodeficiency Virus Type 1 Reverse Transcriptase
|
journal
|
November 2003 |
Analysis of mutations at position 184 in reverse transcriptase of human immunodeficiency virus type 1
|
journal
|
July 1995 |
The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptase
|
journal
|
April 1998 |
Increased polymerase fidelity of the 3TC-resistant variants of HIV-1 reverse transcriptase
|
journal
|
August 1997 |
Human Immunodeficiency Virus Type 1 Expressing the Lamivudine‐Associated M184V Mutation in Reverse Transcriptase Shows Increased Susceptibility to Adefovir and Decreased Replication Capability In Vitro
|
journal
|
January 1999 |
Tenofovir Resistance and Resensitization
|
journal
|
November 2003 |
Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC †
|
journal
|
August 1997 |
The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase 1 1Edited by A. R. Fersht
|
journal
|
July 2000 |
Human Immunodeficiency Virus Type-1 Reverse Transcriptase: CONTRIBUTION OF MET-184 TO BINDING OF NUCLEOSIDE 5′-TRIPHOSPHATE
|
journal
|
June 1996 |
Mechanistic Studies Examining the Efficiency and Fidelity of DNA Synthesis by the 3TC-Resistant Mutant (184V) of HIV-1 Reverse Transcriptase †
|
journal
|
July 1999 |
Structural basis for the binding and incorporation of nucleotide analogs with L-stereochemistry by human DNA polymerase
|
journal
|
July 2014 |
Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ
|
journal
|
June 2015 |
Mechanistic studies show that (-)-FTC-TP is a better inhibitor of HIV-1 reverse transcriptase than 3TC-TP
|
journal
|
September 1999 |
Pre-Steady-State Kinetic Analysis of the Incorporation of Anti-HIV Nucleotide Analogs Catalyzed by Human X- and Y-Family DNA Polymerases
|
journal
|
November 2010 |
Presteady State Kinetic Investigation of the Incorporation of Anti-Hepatitis B Nucleotide Analogues Catalyzed by Noncanonical Human DNA Polymerases
|
journal
|
December 2011 |
Structural and kinetic insights into binding and incorporation of L-nucleotide analogs by a Y-family DNA polymerase
|
journal
|
August 2014 |
Structural basis for the D-stereoselectivity of human DNA polymerase β
|
journal
|
April 2017 |
Visualizing the Molecular Interactions of a Nucleotide Analog, GS-9148, with HIV-1 Reverse Transcriptase–DNA Complex
|
journal
|
April 2010 |
Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance
|
journal
|
October 2009 |
Structure of a Covalently Trapped Catalytic Complex of HIV-1 Reverse Transcriptase: Implications for Drug Resistance
|
journal
|
November 1998 |
Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta -branched amino acids
|
journal
|
August 1999 |
Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir
|
journal
|
April 2004 |
Structural basis of HIV-1 resistance to AZT by excision
|
journal
|
September 2010 |
Initial appearance of the 184Ile variant in lamivudine-treated patients is caused by the mutational bias of human immunodeficiency virus type 1 reverse transcriptase.
|
journal
|
January 1997 |
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.
|
journal
|
August 1996 |
Human immunodeficiency virus reverse transcriptase and protease sequence database
|
journal
|
January 2003 |
Safety, Pharmacokinetics, and Efficacy of (+/−)-β-2′,3′-Dideoxy-5-Fluoro-3′-Thiacytidine with Efavirenz and Stavudine in Antiretroviral-Naïve Human Immunodeficiency Virus-Infected Patients
|
journal
|
July 2005 |
Telbivudine in the treatment of chronic hepatitis B
|
journal
|
February 2009 |
In Vitro Antiretroviral Activity and In Vitro Toxicity Profile of SPD754, a New Deoxycytidine Nucleoside Reverse Transcriptase Inhibitor for Treatment of Human Immunodeficiency Virus Infection
|
journal
|
February 2006 |
A combination of decreased NRTI incorporation and decreased excision determines the resistance profile of HIV-1 K65R RT
|
journal
|
January 2005 |
Trapping HIV-1 Reverse Transcriptase Before and After Translocation on DNA
|
journal
|
January 2003 |
[20] Processing of X-ray diffraction data collected in oscillation mode
|
book
|
January 1997 |
A neutron-diffraction study of the low-cycle fatigue behaviour of an austenitic stainless steel 316
|
journal
|
August 2010 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
|
journal
|
January 2010 |
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
|
journal
|
February 2021 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
|
text
|
January 2010 |