Patents – Roderick MacKinnon
(2003-2011)

MacKinnon Page · Resources with Additional Information


US 6,641,997 ASSAYS FOR SCREENING COMPOUNDS WHICH INTERACT WITH CATION CHANNEL PROTEINS, MUTANT PROKARYOTIC CATION CHANNEL PROTEINS, AND USES THEREOF – MacKinnon, Roderick; November 4, 2003
Assays for screening potential drugs or agents that can interact and potentially bind to cation channel proteins, and potentially have uses in treating conditions related to the function of cation channel proteins is provided, along with prokaryotic cation channel proteins mutated to mimic eukaryotic cation channels, which can then be used in assays of the present invention.

US 7,405,052 VOLTAGE SENSOR DOMAINS OF VOLTAGE-DEPENDENT ION CHANNEL PROTEINS AND USES THEREOF – MacKinnon, Roderick; et. al.; July 29, 2008
A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.

US 7,888,046 VOLTAGE SENSOR DOMAINS OF VOLTAGE-DEPENDENT ION CHANNEL PROTEINS AND USES THEREOF – MacKinnon, Roderick; et. al.; February 15, 2011
A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.


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